Sodium;acetic acid;3,7-dimethyl-2-oxopurin-6-olate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并嘧啶类
• 英文名称: Sodium;acetic acid;3,7-dimethyl-2-oxopurin-6-olate
• 化学式: C9H11N4NaO4
• 分子量: 262.2
• InChiKey: TYIPBFCVIBTJOV-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  -5.28
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  107
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Sustained release tablet comprising pramipexole
  申请人：Pharmacia Corporation

  公开号：EP2172199A1

  公开（公告）日：2010-04-07

  A sustained - release pharmaceutical composition in a form of an orally deliverable tablet comprising an active pharmaceutical agent having solubility not less than about 10mg/ml, dispersed in a matrix comprising a hydrophilic polymer and a starch having a tensile strength of at least about 0.15kNcm-2 at a solid fraction representative of the tablet.

  一种口服给药片剂形式的缓释药物组合物，包含溶解度不小于约 10 毫克/毫升的活性药剂，分散在由亲水性聚合物和淀粉组成的基质中，在片剂的代表性固体部分拉伸强度至少约为 0.15 千牛顿厘米-2。
• Advanced drug development and manufacturing
  申请人：Los Alamos National Security, LLC

  公开号：EP2511844A2

  公开（公告）日：2012-10-17

  There is described an apparatus for measuring protein characteristics comprising an X-ray fluorescence (XRF) spectrometer comprising a source of polychromatic X-rays, an X-ray detector, a protein, a molecule that has been exposed to and at least weakly binds to the protein, a plurality of X-ray fluorescence signal data obtained by irradiating chemical elements in the protein and molecule with the polychromatic X-rays and a security system for maintaining records for the data from the plurality of X-ray fluorescence signal measurements. There is also described an x-ray microscope for measuring a sample.

  描述了一种测量蛋白质特性的仪器，该仪器包括一个 X 射线荧光 (XRF) 光谱仪，其中包括一个多色 X 射线源、一个 X 射线探测器、一个蛋白质、一个已暴露于该蛋白质并至少与该蛋白质弱结合的分子、通过用多色 X 射线照射蛋白质和分子中的化学元素而获得的多个 X 射线荧光信号数据，以及一个用于维护多个 X 射线荧光信号测量数据记录的安全系统。此外，还介绍了一种用于测量样品的 X 射线显微镜。
• Preservative composition
  申请人：——

  公开号：US20040034042A1

  公开（公告）日：2004-02-19

  The present invention provides, as a composition that is highly safe and superior in preservative properties, comprising (a) a xanthine, (b) a buffer and (c) at least one member selected from sorbic acid, EDTA, and salts thereof. This composition has superior preservative properties so that it inhibits the generation and proliferation of microorganisms even when stored for a long period of time. Furthermore, the present invention provides a method for enhancing the preservative properties of sorbic acid, EDTA, and salts thereof, which are known to have preservative properties, and the preservative properties of compositions containing these ingredients, and provides a method for producing a composition with superior preservative effectiveness.

  本发明提供了一种安全性高、防腐性能优越的组合物，由以下成分组成：(a) 黄嘌呤；(b) 缓冲剂；(c) 至少一种选自山梨酸、乙二胺四乙酸及其盐类的成分。这种组合物具有优异的防腐性能，即使长期储存也能抑制微生物的产生和增殖。此外，本发明还提供了一种增强已知具有防腐性能的山梨酸、乙二胺四乙酸及其盐类的防腐性能以及含有这些成分的组合物的防腐性能的方法，并提供了一种生产具有优异防腐效果的组合物的方法。
• ADVANCED DRUG DEVELOPMENT AND MANUFACTURING
  申请人：Los Alamos National Security, LLC

  公开号：EP2084519A2

  公开（公告）日：2009-08-05
• X-RAY FLUORESCENCE ANALYSIS METHOD
  申请人：Los Alamos National Security, LLC

  公开号：EP2084519B1

  公开（公告）日：2012-08-01