2-Fluoro-7-hydroxy-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione | 97677-12-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: 2-Fluoro-7-hydroxy-2'H,5'H-spiro[fluorene-9,4'-imidazolidine]-2',5'-dione
• 英文别名: 2-fluoro-7-hydroxyspiro[fluorene-9,5'-imidazolidine]-2',4'-dione
• CAS: 97677-12-8
• 化学式: C₁₅H₉FN₂O₃
• 分子量: 284.24
• InChiKey: HZEGOYAJGJJYFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  21
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  78.4
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• COMPOSITIONS AND METHODS OF MODULATING S-NITROSYLATION
  申请人：CASE WESTERN RESERVE UNIVERSITY

  公开号：US20190183861A1

  公开（公告）日：2019-06-20

  A method of treating cardiovascular disorders and diseases in a subject in need therof includes administering to the subject an ADH inhibitor, AKR inhibitor, and/or SNO-CoAR inhibitor at an amount(s) effective to promote S-nitrosylation of proteins in the subject, wherein the ADH inhibitor and/or SNO-CoAR inhibitor is not an ADH3 inhibitor.
• US4537892A
  申请人：——

  公开号：US4537892A

  公开（公告）日：1985-08-27