(1S,3R)-3-aminomethyl-3,5,5-trimethylcyclohexylamine

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (1S,3R)-3-aminomethyl-3,5,5-trimethylcyclohexylamine
• 英文别名: (1S,3R)-3-(aminomethyl)-3,5,5-trimethylcyclohexan-1-amine
• 化学式: C₁₀H₂₂N₂
• 分子量: 170.298
• InChiKey: RNLHGQLZWXBQNY-WPRPVWTQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  52
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  benzyl N-{(1S,3R)-3-[(benzyloxycarbonylamino)methyl]-3,5,5-trimethylcyclohexyl}carbamate 在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 20.0 ℃ 、101.32 kPa 条件下， 反应 12.0h， 以100%的产率得到(1S,3R)-3-aminomethyl-3,5,5-trimethylcyclohexylamine
  参考文献：
  名称：

  对映体纯的异佛尔酮二胺[3-（氨基甲基）-3,5,5-三甲基环己胺]：手性的1,4-二胺结构单元可大规模使用

  摘要：

  异佛尔酮二胺[IPDA，3-（氨基甲基）-3,5,5-三甲基环己胺]是一种手性非C 2对称的1,4-二胺，在工业上大规模生产，是所有四种立体异构体的混合物（顺式/反式约3：1）。从该工业大宗产品开始，制备顺式-IPDA的双甲苯磺酰基，双-Fmoc，双-Boc和双-Z衍生物，在手性固定相上通过HPLC制备纯的顺式对映异构体，并指定描述了分离的对映异构体的绝对构型。我们还报告了一种通过与二苯甲酰基酒石酸成盐对IPDA进行光学拆分的有效方法。后一种方法方便地得到对映体纯的顺式-IPDA 100克。从该对映体纯的1，4-二胺制备了许多萨伦配体，并对其进行了充分表征。制备了一种萨伦配体的镍配合物，并通过X射线晶体学分析。Ni 4 L 4配合物的晶体结构说明了顺式-IPDA对于采用其中氨基-和氨基甲基取代基均位于赤道位置的椅子构象的明显偏好。结果，一个配体分子的两个水杨基亚胺部分不会聚在一个金属离子上，而是充当两个镍离子之间的桥连配体。

  DOI：

  10.1021/jo0613737

文献信息

• POLYAMIDE RESIN AND FILM COMPRISING SAME
  申请人：UBE Industries, Ltd.

  公开号：EP3424981A1

  公开（公告）日：2019-01-09

  Provided is a polyamide resin having excellent heat shrinkability. A polyamide resin which contains three or more types of units, wherein the polyamide resin comprises (A) units derived from a lactam and/or an aminocarboxylic acid, and (B) units derived from an equimolar salt of a diamine and a dicarboxylic acid, wherein (B) the units derived from an equimolar salt of a diamine and a dicarboxylic acid comprise (B-1) units having no alicyclic structure and (B-2) units having an alicyclic structure.

  本发明提供了一种具有优异热收缩性的聚酰胺树脂。一种含有三种或三种以上单元的聚酰胺树脂，其中聚酰胺树脂包括（A）由内酰胺和/或氨基羧酸衍生的单元，以及（B）由二胺和二羧酸的等摩尔盐衍生的单元，其中（B）由二胺和二羧酸的等摩尔盐衍生的单元包括（B-1）无脂环结构的单元和（B-2）有脂环结构的单元。
• POLYAMIDE RESIN AND FILM COMPRISING THE SAME
  申请人：UBE INDUSTRIES, LTD.

  公开号：US20190055403A1

  公开（公告）日：2019-02-21

  Provided is a polyamide resin having excellent heat shrinkability. A polyamide resin which contains three or more types of units, wherein the polyamide resin comprises (A) units derived from a lactam and/or an aminocarboxylic acid, and (B) units derived from an equimolar salt of a diamine and a dicarboxylic acid, wherein (B) the units derived from an equimolar salt of a diamine and a dicarboxylic acid comprise (B-1) units having no alicyclic structure and (B-2) units having an alicyclic structure.
• [EN] CURING AGENTS FOR EPOXY RESINS WITH LOW TENDENCY TO THE FORMATION OF CARBAMATES<br/>[FR] AGENTS DE DURCISSEMENT POUR RÉSINES ÉPOXY PRÉSENTANT UNE FAIBLE TENDANCE À LA FORMATION DE CARBAMATES
  申请人：BASF SE

  公开号：WO2019134824A1

  公开（公告）日：2019-07-11

  The present invention relates to amine-based curing agents for epoxy resins with low tendency to the formation of carbamates. In particular the invention relates to methylcyclohexyl diamine based adducts which are particularly suitable for the curing of epoxy resins in the presence of humidity, e.g. flooring applications, because of their low tendency to the formation of carbamates (blushing). Accordingly, the invention relates to a process for the preparation of a cured epoxy resin by curing a curable composition comprising an epoxy resin and an adduct at a curing temperature in the range of 0°C to 100°C, wherein the adduct is formed by reacting methylcyclohexyl diamine with a diglycidyl ether diol, and wherein the composition is exposed to humidity at least least part of the initial 24h time period of the curing starting with the time mixing epoxy resin and adduct of the composition. The invention also relates to a hardener component, comprising a diluent and a methylcyclohexyl diamine based adduct,wherein the diluent is selected from the group consisting of benzyl alcohol, bisphenol A, and alkyl substituted phenols.