七氯-8-甲酰基萘 | 143617-83-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 中文名称: 七氯-8-甲酰基萘
• 英文名称: heptachloro-8-formylnaphthalene
• 英文别名: 2,3,4,5,6,7,8-Heptachloronaphthalene-1-carbaldehyde
• CAS: 143617-83-8
• 化学式: C₁₁HCl₇O
• 分子量: 397.299
• InChiKey: NBLOWWRAISJCNX-UHFFFAOYSA-N

物化性质

• 沸点：
  454.5±40.0 °C(Predicted)
• 密度：
  1.815±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  七氯-8-甲酰基萘 在 Rh(PPh₃)Cl 作用下， 以 苯甲腈 为溶剂， 反应 7.0h， 以47%的产率得到1,2,3,4,5,6,7-heptachloronaphthalene
  参考文献：
  名称：

  Extensive chlorination of methylnaphthalenes, Friedel-Crafts alkylation of pentachlorobenzene by heptachloro(chloromethyl)naphthalenes, and related results

  摘要：

  The chlorination of 2-methylnaphthalene (1) and 1-methylnaphthalene (12) by means of Silberrad's reagent (initial components: SO2Cl2, S2Cl2, and AlCl3) has been performed. From 1 or 12, the following compounds have been synthesized for first time: nonachloro-3-(chloromethyl)-1,4-dihydronaphthalene (3), nonachloro-7-(chloromethyl)-1,4-dihydronaphthalene (4), perchloro-3-vinylindene (2), perchloro-1-vinylindan, nonachloro-4-(chloromethyl)-1,4-dihydronaphthalene (11), heptachloro-7-(chloromethyl)naphthalene (6), heptachloro-8-(chloromethyl)naphthalene (10), heptachloro-7-methylnaphthalene, heptachloro-8-methylnaphthalene, 2-(bromochloromethyl)heptachloronaphthalene, 1-(bromochloromethyl)heptachloronaphthalene, heptachloro-7-formylnaphthalene (24), heptachloro-8-formylnaphthalene (26), (2-heptachloronaphthyl) (pentachlorophenyl)methane (17), and (1-heptachloronaphthyl) (pentachlorophenyl)methane (20). Silberrad's reagent interconverts dihydronaphthalenes 3 and 4. The AlCl3-promoted Friedel-Crafts alkylation of pentachlorobenzene (16) by naphthalenes 6 and 10, giving diarylmethanes 17 and 20, respectively, takes place in mild conditions (refluxing CS2) although the substrate and the alkylating agents are highly crowded polychloro compounds. By heating (100-degrees-C) a mixture of 17, 16, and AlCl3, 1H-heptachloronaphthalene (18) and bis(pentachlorophenyl)methane were obtained. Aldehyde 24, treated with Rh(PPh3)3Cl, gave 2H-heptachloronaphthalene, which was prepared in pure form for the first time. Under similar treatment, aldehyde 26 gave 18. The X-ray structures of indene 2 and dihydronaphthalene 11 are reported and discussed. Some probable mechanisms, as ell as IR, UV, and H-1 NMR spectra data of the compounds synthesized, are presented.

  DOI：

  10.1021/jo00047a026
• 作为产物：
  描述：

  2-甲基萘 在 二氯化二硫 、 三氯化铝 、 磺酰氯 、 硫酸 、 溴 、 tin(ll) chloride 作用下， 以 1,4-二氧六环 、 四氯化碳 为溶剂， 反应 131.25h， 生成 七氯-8-甲酰基萘
  参考文献：
  名称：

  Extensive chlorination of methylnaphthalenes, Friedel-Crafts alkylation of pentachlorobenzene by heptachloro(chloromethyl)naphthalenes, and related results

  摘要：

  The chlorination of 2-methylnaphthalene (1) and 1-methylnaphthalene (12) by means of Silberrad's reagent (initial components: SO2Cl2, S2Cl2, and AlCl3) has been performed. From 1 or 12, the following compounds have been synthesized for first time: nonachloro-3-(chloromethyl)-1,4-dihydronaphthalene (3), nonachloro-7-(chloromethyl)-1,4-dihydronaphthalene (4), perchloro-3-vinylindene (2), perchloro-1-vinylindan, nonachloro-4-(chloromethyl)-1,4-dihydronaphthalene (11), heptachloro-7-(chloromethyl)naphthalene (6), heptachloro-8-(chloromethyl)naphthalene (10), heptachloro-7-methylnaphthalene, heptachloro-8-methylnaphthalene, 2-(bromochloromethyl)heptachloronaphthalene, 1-(bromochloromethyl)heptachloronaphthalene, heptachloro-7-formylnaphthalene (24), heptachloro-8-formylnaphthalene (26), (2-heptachloronaphthyl) (pentachlorophenyl)methane (17), and (1-heptachloronaphthyl) (pentachlorophenyl)methane (20). Silberrad's reagent interconverts dihydronaphthalenes 3 and 4. The AlCl3-promoted Friedel-Crafts alkylation of pentachlorobenzene (16) by naphthalenes 6 and 10, giving diarylmethanes 17 and 20, respectively, takes place in mild conditions (refluxing CS2) although the substrate and the alkylating agents are highly crowded polychloro compounds. By heating (100-degrees-C) a mixture of 17, 16, and AlCl3, 1H-heptachloronaphthalene (18) and bis(pentachlorophenyl)methane were obtained. Aldehyde 24, treated with Rh(PPh3)3Cl, gave 2H-heptachloronaphthalene, which was prepared in pure form for the first time. Under similar treatment, aldehyde 26 gave 18. The X-ray structures of indene 2 and dihydronaphthalene 11 are reported and discussed. Some probable mechanisms, as ell as IR, UV, and H-1 NMR spectra data of the compounds synthesized, are presented.

  DOI：

  10.1021/jo00047a026

文献信息

• Extensive chlorination of methylnaphthalenes, Friedel-Crafts alkylation of pentachlorobenzene by heptachloro(chloromethyl)naphthalenes, and related results
  作者：R. Garcia、J. Riera、J. Carilla、L. Julia、E. Molins、C. Miravitlles

  DOI：10.1021/jo00047a026

  日期：1992.10

  The chlorination of 2-methylnaphthalene (1) and 1-methylnaphthalene (12) by means of Silberrad's reagent (initial components: SO2Cl2, S2Cl2, and AlCl3) has been performed. From 1 or 12, the following compounds have been synthesized for first time: nonachloro-3-(chloromethyl)-1,4-dihydronaphthalene (3), nonachloro-7-(chloromethyl)-1,4-dihydronaphthalene (4), perchloro-3-vinylindene (2), perchloro-1-vinylindan, nonachloro-4-(chloromethyl)-1,4-dihydronaphthalene (11), heptachloro-7-(chloromethyl)naphthalene (6), heptachloro-8-(chloromethyl)naphthalene (10), heptachloro-7-methylnaphthalene, heptachloro-8-methylnaphthalene, 2-(bromochloromethyl)heptachloronaphthalene, 1-(bromochloromethyl)heptachloronaphthalene, heptachloro-7-formylnaphthalene (24), heptachloro-8-formylnaphthalene (26), (2-heptachloronaphthyl) (pentachlorophenyl)methane (17), and (1-heptachloronaphthyl) (pentachlorophenyl)methane (20). Silberrad's reagent interconverts dihydronaphthalenes 3 and 4. The AlCl3-promoted Friedel-Crafts alkylation of pentachlorobenzene (16) by naphthalenes 6 and 10, giving diarylmethanes 17 and 20, respectively, takes place in mild conditions (refluxing CS2) although the substrate and the alkylating agents are highly crowded polychloro compounds. By heating (100-degrees-C) a mixture of 17, 16, and AlCl3, 1H-heptachloronaphthalene (18) and bis(pentachlorophenyl)methane were obtained. Aldehyde 24, treated with Rh(PPh3)3Cl, gave 2H-heptachloronaphthalene, which was prepared in pure form for the first time. Under similar treatment, aldehyde 26 gave 18. The X-ray structures of indene 2 and dihydronaphthalene 11 are reported and discussed. Some probable mechanisms, as ell as IR, UV, and H-1 NMR spectra data of the compounds synthesized, are presented.