N,N'-dimethyl-3,12-diaza-6,9-dioxatetradecane-1,14-diol

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N'-dimethyl-3,12-diaza-6,9-dioxatetradecane-1,14-diol
• 英文别名: 4,13-Diaza-1,7,10,15-tetraoxapentadecane, 4,13-dimethyl-；2-[2-[2-[2-[2-hydroxyethyl(methyl)amino]ethoxy]ethoxy]ethyl-methylamino]ethanol
• 化学式: C₁₂H₂₈N₂O₄
• 分子量: 264.365
• InChiKey: ASHDHMFGVHEIBA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  18
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  65.4
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  N,N'-dimethyl-3,12-diaza-6,9-dioxatetradecane-1,14-diol 、 2,2'-bis(chloromethyl)-4,4'-bis(dimethylamine)biphenyl 在 sodium hydride 、 sodium iodide 作用下， 以 四氢呋喃 为溶剂， 反应 20.0h， 以67%的产率得到2,2'-tetramethylbenzidine-N,N'-dimethyl-6,15-diaza-22-crown-6
  参考文献：
  名称：

  Redox-active aza-crown ethers derived from biphenyl. electrochemical and solution studies of complexation

  摘要：

  Two new ligands 4 and 5, containing in their structures aza-crown ethers moieties in addition to tetramethylbenzidine units, have been prepared. Their ability to complex transition metal cations has been studied by NMR and electrochemical techniques. Ligand 5 gives rise to two diastereoisomeric complexes with Cd(NO3)(2). (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(99)00988-6
• 作为产物：
  描述：

  N-甲基-2-羟基乙胺 、 1,2-二(2-氯乙氧基)乙烷 反应 40.0h， 以91%的产率得到N,N'-dimethyl-3,12-diaza-6,9-dioxatetradecane-1,14-diol
  参考文献：
  名称：

  Redox-active aza-crown ethers derived from biphenyl. electrochemical and solution studies of complexation

  摘要：

  Two new ligands 4 and 5, containing in their structures aza-crown ethers moieties in addition to tetramethylbenzidine units, have been prepared. Their ability to complex transition metal cations has been studied by NMR and electrochemical techniques. Ligand 5 gives rise to two diastereoisomeric complexes with Cd(NO3)(2). (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(99)00988-6

文献信息

• Redox-active aza-crown ethers derived from biphenyl. electrochemical and solution studies of complexation
  作者：Ana M. Costero、Elena Monrabal、Francisco Sanjuan、Ramón Martínez-Máñez、Miguel Padilla-Tosta、Teresa Pardo、Juan Soto

  DOI：10.1016/s0040-4020(99)00988-6

  日期：1999.12

  Two new ligands 4 and 5, containing in their structures aza-crown ethers moieties in addition to tetramethylbenzidine units, have been prepared. Their ability to complex transition metal cations has been studied by NMR and electrochemical techniques. Ligand 5 gives rise to two diastereoisomeric complexes with Cd(NO3)(2). (C) 1999 Elsevier Science Ltd. All rights reserved.