A dosage form with a first portion and a second portion. The first portion can be an immediate release portion and can comprise a pain reliever, which can be naproxen or naproxen sodium. The second portion can be an extended release portion and can comprise pseudoephedrine or a pharmaceutically acceptable salt thereof and/or dextromethorphan or a pharmaceutically acceptable salt thereof. The dosage form can optionally comprise a stabilizing agent. The dosage form can be adapted to maintain a therapeutically effective amount of pain reliever, pseudoephedrine, or a pharmaceutically acceptable salt thereof, and/or dextromethorphan, or a pharmaceutically acceptable salt thereof, for at least eight hours.
一种具有第一部分和第二部分的剂型。第一部分可以是速释部分,包含一种止痛剂,可以是
萘普生或
萘普生钠。第二部分可以是缓释部分,可以包括伪
麻黄碱或其药学上可接受的盐和/或
右美沙芬或其药学上可接受的盐。该剂型可选择包含一种稳定剂。该剂型可使止痛剂、伪
麻黄碱或其药学上可接受的盐和/或
右美沙芬或其药学上可接受的盐的治疗有效量维持至少八小时。