disodium 6,6'-[1,3-phenylenebis(carbonylimino)]bis(1-naphthalenesulfonate)

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: disodium 6,6'-[1,3-phenylenebis(carbonylimino)]bis(1-naphthalenesulfonate)
• 化学式: C₂₈H₁₈N₂O₈S₂*2Na
• 分子量: 620.571
• InChiKey: BDRORCVZPFZYAR-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  1.31
• 重原子数：
  41.0
• 可旋转键数：
  6.0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  172.6
• 氢给体数：
  2.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  disodium 6,6'-[1,3-phenylenebis(carbonylimino)]bis(1-naphthalenesulfonate) 、 scandium tris(trifluoromethanesulfonate) 以 水 为溶剂， 反应 1.0h， 以58%的产率得到scandium sodium bis{6,6 '-[ 1 ,3-phenylenebis-(carbonylimino)]bis(1-naphthalenesulfonate)}
  参考文献：
  名称：

  Removal of Acidic or Basic α-Amino Acids in Water by Poorly Water Soluble Scandium Complexes

  摘要：

  To recognize alpha-amino acids with highly polar side chains in water, poorly water soluble scandium complexes with both Lewis acidic and basic portions were synthesized as artificial receptors. A suspension of some of these receptor molecules in an alpha-amino acid solution could remove acidic and basic alpha-amino acids from the solution. The compound most efficient at preferentially removing basic alpha-amino acids (arginine, histidine, and lysine) was the receptor with 7,7'-[1,3-phenylenebis(carbonylimino)]bis(2-naphthalenesulfonate) as the ligand. The neutral a-amino acids were barely removed by these receptors. Removal experiments using a mixed amino acid solution generally gave results similar to those obtained using solutions containing a single amino acid. The results demonstrated that the scandium complex receptors were useful for binding acidic and basic alpha-amino acids.

  DOI：

  10.1021/jo301739s
• 作为产物：
  描述：

  6-氨基-1-萘磺酸 、 间苯二甲酰氯 在 sodium carbonate 作用下， 以 氯仿 、 水 为溶剂， 反应 18.0h， 以86%的产率得到disodium 6,6'-[1,3-phenylenebis(carbonylimino)]bis(1-naphthalenesulfonate)
  参考文献：
  名称：

  Removal of Acidic or Basic α-Amino Acids in Water by Poorly Water Soluble Scandium Complexes

  摘要：

  To recognize alpha-amino acids with highly polar side chains in water, poorly water soluble scandium complexes with both Lewis acidic and basic portions were synthesized as artificial receptors. A suspension of some of these receptor molecules in an alpha-amino acid solution could remove acidic and basic alpha-amino acids from the solution. The compound most efficient at preferentially removing basic alpha-amino acids (arginine, histidine, and lysine) was the receptor with 7,7'-[1,3-phenylenebis(carbonylimino)]bis(2-naphthalenesulfonate) as the ligand. The neutral a-amino acids were barely removed by these receptors. Removal experiments using a mixed amino acid solution generally gave results similar to those obtained using solutions containing a single amino acid. The results demonstrated that the scandium complex receptors were useful for binding acidic and basic alpha-amino acids.

  DOI：

  10.1021/jo301739s

文献信息

• Removal of Acidic or Basic α-Amino Acids in Water by Poorly Water Soluble Scandium Complexes
  作者：Nobuyuki Hayashi、Shigeki Jin、Tomomi Ujihara

  DOI：10.1021/jo301739s

  日期：2012.11.2

  To recognize alpha-amino acids with highly polar side chains in water, poorly water soluble scandium complexes with both Lewis acidic and basic portions were synthesized as artificial receptors. A suspension of some of these receptor molecules in an alpha-amino acid solution could remove acidic and basic alpha-amino acids from the solution. The compound most efficient at preferentially removing basic alpha-amino acids (arginine, histidine, and lysine) was the receptor with 7,7'-[1,3-phenylenebis(carbonylimino)]bis(2-naphthalenesulfonate) as the ligand. The neutral a-amino acids were barely removed by these receptors. Removal experiments using a mixed amino acid solution generally gave results similar to those obtained using solutions containing a single amino acid. The results demonstrated that the scandium complex receptors were useful for binding acidic and basic alpha-amino acids.