(R)-2-[N-(1-phenylethyl)amino]-1-cyclopentenedithiocarboxylic acid

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (R)-2-[N-(1-phenylethyl)amino]-1-cyclopentenedithiocarboxylic acid
• 英文别名: 2-[[(1R)-1-phenylethyl]amino]cyclopentene-1-carbodithioic acid
• 化学式: C₁₄H₁₇NS₂
• 分子量: 263.428
• InChiKey: BKWCERXTTBJTDZ-SNVBAGLBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  45.1
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2(5H)-呋喃酮 、 (R)-2-[N-(1-phenylethyl)amino]-1-cyclopentenedithiocarboxylic acid 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 24.0h， 以65%的产率得到4,5-dihydro-4-{[2'-((R)-N-α-methylbenzylamino)-1'-cyclopenten-1'-yl](thiocarbonyl)thio}-2(3H)-furanone
  参考文献：
  名称：

  On the easy oxidation of (R)-2-[N-(1-phenylethyl)amino]-1-cyclopentenedithiocarboxylic acid to its disulfide dimer

  摘要：

  The physical and spectroscopic data of (R)-2-[N-(1-phenylethyl)amino]-1-cyclopentenedithiocarboxylic acid are reviewed and the synthesis of (R)-di-[2(N-(1-phenylethyl)amino]-1-cyclopentenedithiocarboxylic acid disulfide is described. The product resulting from the conjugate addition of the dithioacid to 2(5H)-furanone is also characterised. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(99)00354-7
• 作为产物：
  描述：

  R(+)-alpha-甲基苄胺 、 2-氨基-1-环戊烯-1-二硫代甲酸 以 甲醇 为溶剂， 反应 4.5h， 以53%的产率得到(R)-2-[N-(1-phenylethyl)amino]-1-cyclopentenedithiocarboxylic acid
  参考文献：
  名称：

  Two new chiral equivalents of H2S: a thio- and a dithiocarboxylic acid

  摘要：

  The syntheses of the two new chiral mercapto derivatives (R)-2-[N-(1-phenylethyl)amino]-1-cyclopentenedithiocarboxylic acid, 5, and (1S,4R)-1-(4,7,7-trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane) thiocarboxylic acid, 9, are described through easy transformations in good yields. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/0957-4166(96)00334-5

文献信息

• On the easy oxidation of (R)-2-[N-(1-phenylethyl)amino]-1-cyclopentenedithiocarboxylic acid to its disulfide dimer
  作者：Raymundo Cea-Olivares、Verónica Garcı́a-Montalvo、Simón Hernández-Ortega、Cristina Rodrı́guez-Narváez、Patricia Garcı́a y Garcı́a、Marcela López-Cardoso、Pedro de March、Lluı̈sa González、Laia Elias、Marta Figueredo、Josep Font

  DOI：10.1016/s0957-4166(99)00354-7

  日期：1999.8

  The physical and spectroscopic data of (R)-2-[N-(1-phenylethyl)amino]-1-cyclopentenedithiocarboxylic acid are reviewed and the synthesis of (R)-di-[2(N-(1-phenylethyl)amino]-1-cyclopentenedithiocarboxylic acid disulfide is described. The product resulting from the conjugate addition of the dithioacid to 2(5H)-furanone is also characterised. (C) 1999 Published by Elsevier Science Ltd. All rights reserved.
• Two new chiral equivalents of H2S: a thio- and a dithiocarboxylic acid
  作者：Pedro de March、Marta Figueredo、Josep Font、Lluïsa González、Antonio Salgado

  DOI：10.1016/0957-4166(96)00334-5

  日期：1996.9

  The syntheses of the two new chiral mercapto derivatives (R)-2-[N-(1-phenylethyl)amino]-1-cyclopentenedithiocarboxylic acid, 5, and (1S,4R)-1-(4,7,7-trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane) thiocarboxylic acid, 9, are described through easy transformations in good yields. Copyright (C) 1996 Elsevier Science Ltd