(4R,5R)-2,2-dimethyl-α,α,α',α'-tetrakis[6-(benzyloxy)-2-naphthyl]-1,3-dioxolan-4,5-dimethanol

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (4R,5R)-2,2-dimethyl-α,α,α',α'-tetrakis[6-(benzyloxy)-2-naphthyl]-1,3-dioxolan-4,5-dimethanol
• 英文别名: [(4R,5R)-5-[hydroxy-bis(6-phenylmethoxynaphthalen-2-yl)methyl]-2,2-dimethyl-1,3-dioxolan-4-yl]-bis(6-phenylmethoxynaphthalen-2-yl)methanol
• 化学式: C₇₅H₆₂O₈
• 分子量: 1091.31
• InChiKey: BLPKFFCCKOKJTD-NKCYNRQTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  16.1
• 重原子数：
  83
• 可旋转键数：
  18
• 环数：
  13.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  95.8
• 氢给体数：
  2
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  (-)-二甲基-2,3-邻异丙亚基-L-酒石酸酯 、 2-苄氧基-6-溴萘 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 38.75h， 以11%的产率得到(4R,5R)-2,2-dimethyl-α,α,α',α'-tetrakis[6-(benzyloxy)-2-naphthyl]-1,3-dioxolan-4,5-dimethanol
  参考文献：
  名称：

  A New High Twisting Power Material for Use as a Single Asymmetric Dopant in Cholesteric Displays with a Temperature Independence of the Helical Twisting Power

  摘要：

  The synthesis of a novel chiral non-racemic TADDOL derivative is presented and discussed. When the material is placed in a suitable nematic host it forms a chiral nematic phase which has an independence of the helical twisting power (HTP) with temperature. The observed HTP is approximately twice as large as HTPs found in conventional chiral additives, and the independence of the HTP is seen over a 90degreesC temperature range. The HTP as a function of temperature may be modified by the addition of both liquid crystalline and non liquid crystalline achiral additives. The material is unique in that it is also soluble in commercial nematic host materials and has proven to be extremely robust in both thermal and photochemical testing.

  DOI：

  10.1080/15421400490435936

文献信息

• Chiral additives for cholesteric displays
  申请人：——

  公开号：US20020187281A1

  公开（公告）日：2002-12-12

  A unique class of chiral additive materials is disclosed for use in cholesteric displays that possess a helical twist power substantially independent of temperature. The additives have a solubility and a helical twist power large enough to be used as a single chiral component with little dilution of the physical properties of the nematic liquid crystal host mixture. The chiral additives may be used in combination with non-chiral additives to provide a helical twisting power substantially independent of temperature suitable for cholesteric displays.

  本文披露了一类独特的手性添加剂材料，用于胆甾醇显示器，具有与温度基本无关的螺旋扭曲功率。这些添加剂具有足够的溶解度和螺旋扭曲功率，可以作为单一手性组分使用，对向列相液晶主混合物的物理性质几乎没有稀释作用。这些手性添加剂可以与非手性添加剂结合使用，提供与温度基本无关的螺旋扭曲功率，适用于胆甾醇显示器。
• US6830789B2
  申请人：——

  公开号：US6830789B2

  公开（公告）日：2004-12-14
• [EN] CHIRAL ADDITIVES FOR CHOLESTERIC DISPLAYS<br/>[FR] ADDITIFS CHIRAUX POUR AFFICHAGES CHOLESTERIQUES
  申请人：KENT DISPLAYS INC

  公开号：WO2001096494A1

  公开（公告）日：2001-12-20

  A unique class of chiral additive materials is disclosed for use in cholesteric displays that possess a helical twist power substantially independent of temperature. The additives have a solubility and a helical twist power large enough to be used as a single chiral component with little dilution of the physical properties of the nematic liquid crystal host mixture. The chiral additives may be used in combination with non-chiral additives to provide a helical twisting power substantially independent of temperature suitable for cholesteric displays.
• A New High Twisting Power Material for Use as a Single Asymmetric Dopant in Cholesteric Displays with a Temperature Independence of the Helical Twisting Power
  作者：Alexander J. Seed、Margaret E. Walsh、J. William Doane、Asad Khan

  DOI：10.1080/15421400490435936

  日期：2004.1

  The synthesis of a novel chiral non-racemic TADDOL derivative is presented and discussed. When the material is placed in a suitable nematic host it forms a chiral nematic phase which has an independence of the helical twisting power (HTP) with temperature. The observed HTP is approximately twice as large as HTPs found in conventional chiral additives, and the independence of the HTP is seen over a 90degreesC temperature range. The HTP as a function of temperature may be modified by the addition of both liquid crystalline and non liquid crystalline achiral additives. The material is unique in that it is also soluble in commercial nematic host materials and has proven to be extremely robust in both thermal and photochemical testing.