(25R)-26-O-[(β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl)]-14-hydroxy-furost-5,20(22)-diene 3-O-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: (25R)-26-O-[(β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl)]-14-hydroxy-furost-5,20(22)-diene 3-O-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside
• 英文别名: furostanol saponin ophiopogonin J
• 化学式: C₅₁H₈₂O₂₃
• 分子量: 1063.2
• InChiKey: HUJJWJQZLQMMBG-MLFCPERGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.94
• 重原子数：
  74.0
• 可旋转键数：
  15.0
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  366.29
• 氢给体数：
  14.0
• 氢受体数：
  23.0

反应信息

• 作为反应物：
  描述：

  (25R)-26-O-[(β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl)]-14-hydroxy-furost-5,20(22)-diene 3-O-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside 在 盐酸 作用下， 以 1,4-二氧六环 、 水 为溶剂， 反应 1.5h， 生成 L-鼠李糖 、 葡萄糖
  参考文献：
  名称：

  Two new furostanol saponins from the fibrous root ofOphiopogon japonicus

  摘要：

  Two new furostanol saponins ophiopogonins J (1) and K (2) were isolated from the fibrous roots of Ophiopogon japonicus. The structures of 1 and 2 were established as (25R)-26-O-[(-d-glucopyranosyl-(12)--d-glucopyranosyl)]-14-hydroxy-furost-5,20(22)-diene 3-O-[-l-rhamnopyranosyl-(12)]--d-glucopyranoside (1), and (25R)-26-O-[(-d-glucopyranosyl-(12)--d-glucopyranosyl)]-furost-5,20(22)-diene 3-O--l-rhamnopyranosyl-(12)[(-d-xylopyranosyl-(14)--d-glucopyranoside)] (2) on the basis of spectroscopic means including HRESIMS, 1D, and 2D NMR experiments.

  DOI：

  10.1080/10286020.2013.861822

文献信息

• Two new furostanol saponins from the fibrous root of<i>Ophiopogon japonicus</i>
  作者：Zhi-Yun Kang、Meng-Jia Zhang、Jian-Xin Wang、Jian-Xun Liu、Chang-Ling Duan、De-Quan Yu

  DOI：10.1080/10286020.2013.861822

  日期：2013.12

  Two new furostanol saponins ophiopogonins J (1) and K (2) were isolated from the fibrous roots of Ophiopogon japonicus. The structures of 1 and 2 were established as (25R)-26-O-[(-d-glucopyranosyl-(12)--d-glucopyranosyl)]-14-hydroxy-furost-5,20(22)-diene 3-O-[-l-rhamnopyranosyl-(12)]--d-glucopyranoside (1), and (25R)-26-O-[(-d-glucopyranosyl-(12)--d-glucopyranosyl)]-furost-5,20(22)-diene 3-O--l-rhamnopyranosyl-(12)[(-d-xylopyranosyl-(14)--d-glucopyranoside)] (2) on the basis of spectroscopic means including HRESIMS, 1D, and 2D NMR experiments.