6-[6-(benzyloxy)-2H-1,3-benzoxazin-3(4H)-yl]hexan-1-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 英文名称: 6-[6-(benzyloxy)-2H-1,3-benzoxazin-3(4H)-yl]hexan-1-ol
• 英文别名: 6-(6-Phenylmethoxy-2,4-dihydro-1,3-benzoxazin-3-yl)hexan-1-ol；6-(6-phenylmethoxy-2,4-dihydro-1,3-benzoxazin-3-yl)hexan-1-ol
• 化学式: C₂₁H₂₇NO₃
• 分子量: 341.45
• InChiKey: XPBRZAVVGFGFEJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  25
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  41.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  6-[6-(benzyloxy)-2H-1,3-benzoxazin-3(4H)-yl]hexan-1-ol 、 酞菁二氯化硅 在 sodium hydride 作用下， 以 甲苯 为溶剂， 反应 24.0h， 以22%的产率得到
  参考文献：
  名称：

  Synthesis and electrochemistry of non-aggregated axially disubstituted silicon phthalocyanines bearing benzoxazin substituents

  摘要：

  In this study, the new 2-{2-[6-(benzyloxy)-2H-1,3-benzoxazin-3(4H)-yl] ethoxy} ethanol, 6-[6-(benzyloxy)-2H-1,3-benzoxazin-3(4H)-yl] hexan-1-ol have been synthesized. Then, a series of new two axially disubstituted silicon(IV) phthalocyanines (SiPcs) bearing benzoxazin substituents have been synthesized and characterized. Synthesized axially di-substituted SiPcs showed good solubility in many organic solvents. The aggregation behavior of SiPcs was examined in different solvents and concentrations in DMSO. In all studied solvents, SiPcs were non-aggregated. Electrochemical properties of axially disubstituted SiPcs were determined with voltammetric (CV and SWV) measurements. Cyclic voltammetry showed three reduction couples and one oxidation couple for two axially disubstituted silicon(IV) phthalocyanines (SiPcs) bearing benzoxazin substituents. (C) 2015 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2015.01.023
• 作为产物：
  描述：

  聚合甲醛 、 6-氨基-1-己醇 、 4-苄氧基苯酚 反应 24.0h， 以40%的产率得到6-[6-(benzyloxy)-2H-1,3-benzoxazin-3(4H)-yl]hexan-1-ol
  参考文献：
  名称：

  Synthesis and electrochemistry of non-aggregated axially disubstituted silicon phthalocyanines bearing benzoxazin substituents

  摘要：

  In this study, the new 2-{2-[6-(benzyloxy)-2H-1,3-benzoxazin-3(4H)-yl] ethoxy} ethanol, 6-[6-(benzyloxy)-2H-1,3-benzoxazin-3(4H)-yl] hexan-1-ol have been synthesized. Then, a series of new two axially disubstituted silicon(IV) phthalocyanines (SiPcs) bearing benzoxazin substituents have been synthesized and characterized. Synthesized axially di-substituted SiPcs showed good solubility in many organic solvents. The aggregation behavior of SiPcs was examined in different solvents and concentrations in DMSO. In all studied solvents, SiPcs were non-aggregated. Electrochemical properties of axially disubstituted SiPcs were determined with voltammetric (CV and SWV) measurements. Cyclic voltammetry showed three reduction couples and one oxidation couple for two axially disubstituted silicon(IV) phthalocyanines (SiPcs) bearing benzoxazin substituents. (C) 2015 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2015.01.023

文献信息

• Synthesis and electrochemistry of non-aggregated axially disubstituted silicon phthalocyanines bearing benzoxazin substituents
  作者：Zekeriya Biyiklioglu、Hüseyin Baş

  DOI：10.1016/j.ica.2015.01.023

  日期：2015.3

  In this study, the new 2-2-[6-(benzyloxy)-2H-1,3-benzoxazin-3(4H)-yl] ethoxy} ethanol, 6-[6-(benzyloxy)-2H-1,3-benzoxazin-3(4H)-yl] hexan-1-ol have been synthesized. Then, a series of new two axially disubstituted silicon(IV) phthalocyanines (SiPcs) bearing benzoxazin substituents have been synthesized and characterized. Synthesized axially di-substituted SiPcs showed good solubility in many organic solvents. The aggregation behavior of SiPcs was examined in different solvents and concentrations in DMSO. In all studied solvents, SiPcs were non-aggregated. Electrochemical properties of axially disubstituted SiPcs were determined with voltammetric (CV and SWV) measurements. Cyclic voltammetry showed three reduction couples and one oxidation couple for two axially disubstituted silicon(IV) phthalocyanines (SiPcs) bearing benzoxazin substituents. (C) 2015 Elsevier B.V. All rights reserved.