dihexyl trithiocarbonate

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫基化合物
• 英文名称: dihexyl trithiocarbonate
• 英文别名: di-n-hexyl trithiocarbonate；di-n-hexyl carbonotrithioate；Bis(hexylsulfanyl)methanethione
• 化学式: C₁₃H₂₆S₃
• 分子量: 278.547
• InChiKey: SECNJHOADFQCGC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  16
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  82.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  溴己烷 、 potassium trithiocarbonate 以 N,N-二甲基甲酰胺 为溶剂， 反应 12.0h， 以90%的产率得到dihexyl trithiocarbonate
  参考文献：
  名称：

  K₃PO₄-mediated one-pot synthesis of symmetrical trithiocarbonates

  摘要：

  A new procedure has been developed for synthesis of symmetrical trithiocarbonates by one-pot reaction of carbon disulfide, and various alkyl halides in dimethylformamide using K3PO4 as an inexpensive and effective reagent.

  DOI：

  10.1080/17415993.2012.731064

文献信息

• Superbasic system CsOH/DMSO as a reagent for a fast one-step synthesis of symmetrical dialkyl trithiocarbonates
  作者：Ali Yousefi

  DOI：10.1080/17415993.2015.1079912

  日期：2015.11.2

  Symmetrical dialkyl trithiocarbonates were readily synthesized in excellent yields by one-step reaction of carbon disulfide and various alkyl halides under mild reaction conditions in the presence of cesium hydroxide as a super basic system. This method provides a synthesis of symmetrical dialkyl trithiocarbonates in short reaction times without the use of highly toxic starting materials. GRAPHICAL

  在氢氧化铯作为超碱性体系存在下，在温和的反应条件下，通过二硫化碳和各种烷基卤化物的一步反应，可以很容易地以优异的收率合成对称的二烷基三硫代碳酸酯。该方法提供了在短反应时间内合成对称的三硫代碳酸二烷基酯，而无需使用剧毒的起始材料。图形概要
• A Facile KF/Al₂O₃-mediated, One-pot Synthesis of Symmetrical Trithiocarbonates from Alkyl Halides and Carbon Disulfide
  作者：Barahman Movassagh、Mohammad Soleiman-Beigi、Mohammad Nazari

  DOI：10.1246/cl.2008.22

  日期：2008.1.5

  A facile, efficient, and convenient method has been developed for the one-pot synthesis of symmetrical trithiocarbonates from carbon disulfide and various alkyl halides in the presence of KF/Al 2 O 3 in DMF at room temperature.

  已开发出一种简便、高效且方便的方法，用于在室温下在 DMF 中，在 KF/Al 2 O 3 存在下，由二硫化碳和各种烷基卤化物一锅法合成对称的三硫代碳酸酯。
• Polymers and nanogel materials and methods for making and using the same
  申请人：Johnson & Johnson Vision Care, Inc.

  公开号：US10073192B2

  公开（公告）日：2018-09-11

  Provided are compositions comprising a block copolymer of the following formula: [A]-B-[Q], wherein [A] is a polymer that has an affinity for a substrate; B is a linking group comprising an optionally-substituted, polyvalent linking group having a molecular weight of no more than 1000 g/mole; and [Q] comprises a semi-crosslinked, ungelled polymer derived from copolymerization of an ethylenically unsaturated monomer with a poly-functional ethylenically unsaturated monomer. Such block copolymers are cross-linked via the [Q] segment, but not macroscopically gelled. The [Q] segment is hydrophilic and has a degree of polymerization in the range of about 10 to about 10,000. The [A] segment is located on at least one terminal end of said block copolymer, comprises between about 1 and about 200 repeating units. The block copolymer is associated, via the linear substrate associative segment with a surface comprising at least one hydrophobic site, such as a silicone hydrogel. The polymers may be incorporated into a formulation from which the silicone hydrogel is made or may be contacted with the silicone hydrogel post-formation.

  本发明提供了包含下式嵌段共聚物的组合物：[A]-B-[Q]，其中[A]是对底物具有亲和力的聚合物；B 是由任选取代的多价连接基团组成的连接基团，其分子量不超过 1000 克/摩尔；[Q]是由乙烯基不饱和单体与多官能团乙烯基不饱和单体共聚而成的半交联、未胶凝的聚合物。这种嵌段共聚物通过[Q]段交联，但宏观上并不胶凝。Q]段具有亲水性，聚合度在约 10 到约 10,000 之间。A]段位于所述嵌段共聚物的至少一个末端，包含约 1 至约 200 个重复单元。嵌段共聚物通过线性基质连接段与包含至少一个疏水位点的表面（如硅酮水凝胶）连接。聚合物可以加入硅酮水凝胶的配方中，也可以在成型后与硅酮水凝胶接触。
• Non-reactive, hydrophilic polymers having terminal siloxanes and methods for making and using the same
  申请人：Johnson & Johnson Vision Care, Inc.

  公开号：US10301465B2

  公开（公告）日：2019-05-28

  The present invention relates to compositions comprising at least one stable, near-monodisperse, non-reactive hydrophilic polymer comprising in said polymer's backbone, a hydrophilic segment having a degree of polymerization of about 10 to about 1000, and a linear silicone segment at at least one terminal end of said non-reactive hydrophilic polymer, wherein said silicone segment comprises between about 6 and about 200 siloxy units, and said non-reactive hydrophilic polymer is associated, via the linear silicone block with a silicone hydrogel. The non-reactive hydrophilic polymers may be incorporated into the formulation from which the silicone hydrogel is made or may be contacted with the silicone hydrogel post formation.

  本发明涉及包含至少一种稳定的、接近单分散的、非反应性亲水聚合物的组合物，所述聚合物的骨架中包含聚合度约为10至约1000的亲水段，以及位于所述非反应性亲水聚合物至少一个末端的线性硅酮段，其中所述硅酮段包含约6至约200个硅氧基单元，所述非反应性亲水聚合物通过线性硅酮块与硅酮水凝胶相连。非反应性亲水聚合物可以加入硅酮水凝胶的配方中，也可以在硅酮水凝胶形成后与之接触。
• Leung, Man-kit; Hsieh, Dung-Ting; Lee, Kang-Hwa, Journal of Chemical Research - Part S, 1995, # 11, p. 478 - 479
  作者：Leung, Man-kit、Hsieh, Dung-Ting、Lee, Kang-Hwa、Liou, Jia-Chie

  DOI：——

  日期：——