octadecyl sulfamate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫酸及其衍生物
• 英文名称: octadecyl sulfamate
• 英文别名: Sulfamic acid octadecyl ester
• 化学式: C₁₈H₃₉NO₃S
• 分子量: 349.579
• InChiKey: NYVPGHBUIIWTTF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.8
• 重原子数：
  23
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  77.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  硬脂醇 在 氨基磺酰氯 作用下， 以 N,N-二甲基乙酰胺 为溶剂， 生成 octadecyl sulfamate
  参考文献：
  名称：

  碳酸酐酶抑制剂：用脂肪族氨基磺酸盐抑制跨膜，肿瘤相关同工酶IX和胞质同工酶I和II。

  摘要：

  合成了一系列脂族氨基磺酸盐及其分子中结合了环状/多环（甾族）部分的相关衍生物，并将其检测为锌酶碳酸酐酶（CA）的抑制剂，更准确地说，是胞质同工酶CA I和II以及跨膜，肿瘤相关同工酶CA IX。最有效的CA I抑制剂是正十四烷基氨基磺酸盐和一些（取代的）苄基/苯乙基氨基磺酸盐（抑制常数在低微摩尔范围内）。针对CA II，低纳摩尔抑制剂（0.7-3.4 nM）为氨基磺酸正癸酯和上述（取代的）苄基/苯乙基衍生物。还观察到了脱氢表雄酮氨基磺酸盐的羟基/酮衍生物对CA II的有效抑制。有效的CA IX抑制特性，抑制常数范围为9-23 nM，观察到脂族氨基磺酸盐C（10）-C（16）（最有效的抑制剂是正十二烷基衍生物）和（取代的）苄基/苯乙基氨基磺酸盐。三种研究的同工酶对这种类型化合物的抑制谱有很大不同，这使我们希望可以制备CA IX选择性抑制剂（对hCA IX与hCA II的选择性比范围为5-63

  DOI：

  10.1021/jm030911u

文献信息

• Pigment dispersion composition, red colored composition, colored curable composition, color filter for a solid state imaging device and method for producing the same, and solid state imaging device
  申请人：FUJIFILM Corporation

  公开号：EP2392621A2

  公开（公告）日：2011-12-07

  Provided is a pigment dispersion composition suitable for a colored curable composition which enables retaining adhesion capability of a colored pattern and inhibiting the generation of residues, even when a relatively severe development condition is employed. Furthermore, a red colored composition capable of forming a red colored thin film with excellent spectral characteristics. The pigment composition contains an azo pigment represented by the following Formula (1); at least one of acidic functional group-containing organic pigment derivative, anthraquinone derivative, and triazine derivative; and a dispersant, The red colored composition contains a red pigment; a yellow pigment; and a dispersant, in which specific spectral characteristics are satisfied when a colored transmitting film having a thickness of 0.6 µm is formed using the red colored composition.

  本发明提供了一种适用于彩色固化组合物的颜料分散组合物，该组合物即使在相对苛刻的显影条件下也能保持彩色图案的附着能力并抑制残留物的产生。此外，一种红色颜料组合物能够形成具有优异光谱特性的红色薄膜。该颜料组合物包含由下式（1）表示的偶氮颜料；含酸性官能团的有机颜料衍生物、蒽醌衍生物和三嗪衍生物中的至少一种；以及分散剂，其中红色组合物包含红色颜料、黄色颜料和分散剂，当使用该红色组合物形成厚度为 0.6 µm 的彩色透射膜时，可满足特定的光谱特性。
• METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING SULFAMIC ACIDS
  申请人：BUCKMAN LABORATORIES INTERNATIONAL, INC.

  公开号：EP0999746B1

  公开（公告）日：2003-02-19
• PIGMENT DISPERSION COMPOSITION, RED COLORED COMPOSITION, COLORED CURABLE COMPOSITION, COLOR FILTER FOR A SOLID STATE IMAGING DEVICE AND METHOD FOR PRODUCING THE SAME, AND SOLID STATE IMAGING DEVICE
  申请人：TAGUCHI Hiroshi

  公开号：US20110294050A1

  公开（公告）日：2011-12-01

  Provided is a pigment dispersion composition suitable for a colored curable composition which enables retaining adhesion capability of a colored pattern and inhibiting the generation of residues, even when a relatively severe development condition is employed. Furthermore, a red colored composition capable of forming a red colored thin film with excellent spectral characteristics. The pigment composition contains an azo pigment represented by the following Formula (1); at least one of acidic functional group-containing organic pigment derivative, anthraquinone derivative, and triazine derivative; and a dispersant. The red colored composition contains a red pigment; a yellow pigment; and a dispersant, in which specific spectral characteristics are satisfied when a colored transmitting film having a thickness of 0.6 μm is formed using the red colored composition.
• US6103131A
  申请人：——

  公开号：US6103131A

  公开（公告）日：2000-08-15
• US6380182B1
  申请人：——

  公开号：US6380182B1

  公开（公告）日：2002-04-30