1,4,8,11-tetrakis-(2-pyridyl)-1,4,8,11-tetraazacyclotetradecane

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1,4,8,11-tetrakis-(2-pyridyl)-1,4,8,11-tetraazacyclotetradecane
• 英文别名: 1,4,8,11-Tetrapyridin-2-yl-1,4,8,11-tetrazacyclotetradecane；1,4,8,11-tetrapyridin-2-yl-1,4,8,11-tetrazacyclotetradecane
• 化学式: C₃₀H₃₆N₈
• 分子量: 508.669
• InChiKey: FJXBCDYMEVIYFJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  38
• 可旋转键数：
  4
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  64.5
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  1,4,8,11-四氮杂环十四烷 、 2-氟吡啶 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 100.0 ℃ 、800.0 MPa 条件下， 反应 168.0h， 以22%的产率得到1,4,8,11-tetrakis-(2-pyridyl)-1,4,8,11-tetraazacyclotetradecane
  参考文献：
  名称：

  Synthesis of New Armed Cyclopolyamines and Their Selective Extraction Properties for Metal Ions

  摘要：

  A variety of new armed cyclopolyamines were prepared by high pressure SNAr reactions (0.8 GPa, 100 degrees C) of cyclopolyamines with heteroaromatic halides. Certain of these agents show selective extraction properties for Hg2+ and Ag+ ions.

  DOI：

  10.3987/com-94-6952

文献信息

• Synthesis of New Armed Cyclopolyamines and Their Selective Extraction Properties for Metal Ions
  作者：Kiyoshi Matsumoto、Keisuke Fukuyama、Hirokazu Iida、Mitsuo Toda、J. William Lown

  DOI：10.3987/com-94-6952

  日期：——

  A variety of new armed cyclopolyamines were prepared by high pressure SNAr reactions (0.8 GPa, 100 degrees C) of cyclopolyamines with heteroaromatic halides. Certain of these agents show selective extraction properties for Hg2+ and Ag+ ions.
• Molecular Inclusion Crystals of Novel Heterocyclic Host Compounds
  作者：Kiyoshi Matsumoto、Mitsuo Toda、Yukio Ikemi、Akikazu Kakehi、Shiro Hashimoto、Motoo Shiro、Shinichi Otani

  DOI：10.1080/10587259608039375

  日期：1996.2

  Inclusion phenomena of the solvents such as hexane, benzene, and dichloromethane in either the crystals or glassy states of the armed-1,4,8,12-tetrazacyclopentadecanes were observed, whereas only few inclusion was found in the armed 1,4,8,11-tetraazacyclotetradecanes. As further examples of undesigned inclusion hosts, the 1:2 adduct, obtained by Diels-Alder reaction of [2.2]paracyclophane with 4-phenyl-1,2,4-triazoline-3,5-dione, along with the 1:2 adducts from 5-cyano-1,4-diphenylpyridazino[4,5-a]-indolizines and dimethyl acetylenedicarboxylate (DMAD) are described.