syringic acid 4-O-beta-D-glucuronide

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 单宁
• 英文名称: syringic acid 4-O-beta-D-glucuronide
• 英文别名: Syringic acid glucuronide；(2S,3S,4S,5R,6S)-6-(4-carboxy-2,6-dimethoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid
• 化学式: C₁₅H₁₈O₁₁
• 分子量: 374.301
• InChiKey: WOGNQDHJFYPQMD-YGMDGNCASA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  172
• 氢给体数：
  5
• 氢受体数：
  11

反应信息

• 作为产物：
  描述：

  葡醛内酯 在 水 、 氢溴酸 、 溶剂黄146 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 、 silver carbonate 、 potassium hydroxide 作用下， 以 甲醇 、 二氯甲烷 、 丙酮 为溶剂， 反应 71.0h， 生成 syringic acid 4-O-beta-D-glucuronide
  参考文献：
  名称：

  GLUCOSYRINGIC ACID ANALOGS AS SWEETNESS PROFILE MODIFIERS

  摘要：

  本公开提供了包含具有如下式I的结构的化合物的新型甜味剂组合物： 其中R1、R2、R3和R4如本文所述。还提供了通过向产品添加式I的化合物来调节产品的甜味特性的方法，例如饮料产品或食品产品。例如，本文描述的化合物可添加以增加富含甜味剂的饮料的整体甜度；减少高效甜味剂（如甜菊糖A）的甜味起始时间；减少高效甜味剂的苦味、金属味和甘草味等异味；并改善甜味产品的甜味质量。

  公开号：

  US20180020708A1

文献信息

• Glucosyringic acid analogs as sweetness profile modifiers
  申请人：PepsiCo, Inc.

  公开号：US10966447B2

  公开（公告）日：2021-04-06

  The present disclosure provides novel sweetener compositions comprising a compound having a structure according to Formula I: wherein R1, R2, R3, and R4 are described herein. Also provided are methods of modulating sweetness profile of a product by adding a compound of Formula I to the product, such as a beverage product or a food product. For example, the compound described herein can be added to increase the overall sweetness of a nutritive sweetener sweetened beverages; decrease the sweetness time-of-onset for high potency sweeteners such as rebaudioside A; decreasing bitter, metallic and licorice off-notes of high potency sweeteners; and improve the sweet quality of sweetened products.

  本公开提供了新型甜味剂组合物，该组合物包含具有根据式 I 所述结构的化合物：其中 R1、R2、R3 和 R4 已在本文中描述。 还提供了通过向饮料产品或食品等产品中添加式 I 化合物来调节产品甜度曲线的方法。 例如，添加本文所述的化合物可增加营养型甜味剂甜饮料的总体甜度；减少高活性甜味剂（如雷公藤甙 A）的甜味起效时间；减少高活性甜味剂的苦味、金属味和甘草味；以及改善甜味产品的甜味质量。
• [EN] GLUCOSYRINGIC ACID ANALOGS AS SWEETNESS PROFILE MODIFIERS<br/>[FR] ANALOGUES DE L'ACIDE GLUCOSYRINGIQUE EN TANT QUE MODIFICATEURS DU PROFIL ÉDULCORANT
  申请人：PEPSICO INC

  公开号：WO2018017574A1

  公开（公告）日：2018-01-25

  The present disclosure provides novel sweetener compositions comprising a compound having a structure according to Formula (I): wherein R1, R2, R3, and R4 are described herein. Also provided are methods of modulating sweetness profile of a product by adding a compound of Formula (I) to the product, such as a beverage product or a food product. For example, the compound described herein can be added to increase the overall sweetness of a nutritive sweetener sweetened beverages; decrease the sweetness time-ofonset for high potency sweeteners such as rebaudioside A; decreasing bitter, metallic and licorice off-notes of high potency sweeteners; and improve the sweet quality of sweetened products.
• GLUCOSYRINGIC ACID ANALOGS AS SWEETNESS PROFILE MODIFIERS
  申请人：PepsiCo, Inc.

  公开号：US20180020708A1

  公开（公告）日：2018-01-25

  The present disclosure provides novel sweetener compositions comprising a compound having a structure according to Formula I: wherein R 1 , R 2 , R 3 , and R 4 are described herein. Also provided are methods of modulating sweetness profile of a product by adding a compound of Formula I to the product, such as a beverage product or a food product. For example, the compound described herein can be added to increase the overall sweetness of a nutritive sweetener sweetened beverages; decrease the sweetness time-of-onset for high potency sweeteners such as rebaudioside A; decreasing bitter, metallic and licorice off-notes of high potency sweeteners; and improve the sweet quality of sweetened products.

  本公开提供了包含具有如下式I的结构的化合物的新型甜味剂组合物： 其中R1、R2、R3和R4如本文所述。还提供了通过向产品添加式I的化合物来调节产品的甜味特性的方法，例如饮料产品或食品产品。例如，本文描述的化合物可添加以增加富含甜味剂的饮料的整体甜度；减少高效甜味剂（如甜菊糖A）的甜味起始时间；减少高效甜味剂的苦味、金属味和甘草味等异味；并改善甜味产品的甜味质量。