14,15-anhydro-20-hydroxyecdysone (6E)-oxime

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 14,15-anhydro-20-hydroxyecdysone (6E)-oxime
• 英文别名: (2R,3R)-2-[(2S,3R,5R,6E,9R,10R,13R,17S)-2,3-dihydroxy-6-hydroxyimino-10,13-dimethyl-1,2,3,4,5,9,11,12,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-6-methylheptane-2,3,6-triol
• 化学式: C₂₇H₄₃NO₆
• 分子量: 477.642
• InChiKey: NISNRXHXSLWTHW-JIOIZFQDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  34
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  134
• 氢给体数：
  6
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  蜕皮激素 在 盐酸羟胺 作用下， 以 吡啶 为溶剂， 反应 72.0h， 生成 14,15-anhydro-20-hydroxyecdysone (6E)-oxime 、 14,15-anhydro-20-hydroxyecdysone (6Z)-oxime
  参考文献：
  名称：

  Synthesis of 20-hydroxyecdysone oxime, its diacetonide, and their 14,15-anhydro derivatives

  摘要：

  20-Hydroxyecdysone oxime, its diacetonide, and the corresponding 14,15-anhydro derivatives were synthesized. Conditions were found for the preparation of the Z- and E-oximes, and their characteristic H-1 and C-13 NMR parameters were determined.

  DOI：

  10.1134/s1070428006090132

文献信息

• Synthesis of 20-hydroxyecdysone oxime, its diacetonide, and their 14,15-anhydro derivatives
  作者：I. V. Galyautdinov、N. A. Ves’kina、S. R. Afon’kina、L. M. Khalilov、V. N. Odinokov

  DOI：10.1134/s1070428006090132

  日期：2006.9

  20-Hydroxyecdysone oxime, its diacetonide, and the corresponding 14,15-anhydro derivatives were synthesized. Conditions were found for the preparation of the Z- and E-oximes, and their characteristic H-1 and C-13 NMR parameters were determined.