(3R)-N-(3,3-dimethylbutyl)oxan-3-amine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧烷类
• 英文名称: (3R)-N-(3,3-dimethylbutyl)oxan-3-amine
• 化学式: C₁₁H₂₃NO
• 分子量: 185.31
• InChiKey: IJAOJUBTAJZYFI-SNVBAGLBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  21.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• INHALED POWDER FORMULATIONS
  申请人：Genentech, Inc.

  公开号：US20200165260A1

  公开（公告）日：2020-05-28

  Compounds of Formula (00A) and salts thereof, wherein R 1 , R 2 R 3 , R 4 and n are defined herein, are useful as inhibitors of one or more Janus kinases. Also provided are pharmaceutical compositions that include a compound of Formula (00A) and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient.
• THERAPEUTIC COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
  申请人：Genentech, Inc.

  公开号：US20210009599A1

  公开（公告）日：2021-01-14

  Compounds of Formula (I): salts thereof and methods of making and use as Janus kinase inhibitors are described herein.