去甲珠氯噻醇标准品 | 75013-63-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻喃类
• 中文名称: 去甲珠氯噻醇标准品
• 英文名称: Piperazine, 1-(3-(2-chloro-9H-thioxanthen-9-ylidene)propyl)-, (Z)-
• 英文别名: 1-[(3Z)-3-(2-chlorothioxanthen-9-ylidene)propyl]piperazine
• CAS: 75013-63-7；21642-94-4
• 化学式: C₂₀H₂₁ClN₂S
• 分子量: 356.9
• InChiKey: SLTQOJGWYUTULB-BNCCVWRVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.5
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  40.6
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Thioxanthene derivatives for use in the treatment of infectious diseases
  申请人：BKG Pharma ApS

  公开号：EP2301545A1

  公开（公告）日：2011-03-30

  The present invention is directed to certain thioxanthene derivatives and phenothiazine derivatives suitable for use as anti-infective agents, in particular, for treatment of infectious diseases. The invention furthermore relates to compositions comprising said anti-infective agents.

  本发明涉及某些适合用作抗感染剂，特别是用于治疗传染病的噻吨烷衍生物和吩噻嗪衍生物。本发明还涉及包含上述抗感染剂的组合物。
• THIOXANTHENE DERIVATES AS SOLE ANTI-INFECTIVE AGENTS FOR USE IN THE TREATMENT OF INFECTIOUS DISEASES
  申请人：BKG Pharma ApS

  公开号：EP2114406B1

  公开（公告）日：2011-05-25
• THIOXANTHENE DERIVATES USEFUL TO TREAT INFECTIOUS DISEASES
  申请人：Giwercman Birgit Kjældgaard

  公开号：US20100113430A1

  公开（公告）日：2010-05-06

  The present invention is directed to certain thioxanthene derivatives and phenothiazine derivatives suitable for use as anti-infective agents, in particular, for treatment of infectious diseases. The invention furthermore relates to compositions comprising said anti-infective agents.