{[(2'R,4'S,5'R)-5'-vinylquinuclidyl]-2'-methoxy}-1,3,2-dioxaphospholane

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 奎宁环
• 英文名称: {[(2'R,4'S,5'R)-5'-vinylquinuclidyl]-2'-methoxy}-1,3,2-dioxaphospholane
• 英文别名: (2R,4S,5R)-2-(1,3,2-dioxaphospholan-2-yloxymethyl)-5-ethenyl-1-azabicyclo[2.2.2]octane
• 化学式: C₁₂H₂₀NO₃P
• 分子量: 257.269
• InChiKey: RIIZNTYIZGXKOD-SDDRHHMPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  30.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-diethylamino-1,3,2-dioxaphospholane 、 quincoridine 110.0~140.0 ℃ 、266.64 Pa 条件下， 反应 2.0h， 以70%的产率得到{[(2'R,4'S,5'R)-5'-vinylquinuclidyl]-2'-methoxy}-1,3,2-dioxaphospholane
  参考文献：
  名称：

  Quincoridine-based aminophosphite ligands and their Rh(I) and Pd(II) complexes

  摘要：

  New chiral P,N-bidentate ligands containing a quincoridine fragment with a configuration-stable N-donating center were obtained. Coordination of the ligands to Rh(I) and Pd(II) atoms was carried out. Chlorocarbonyl rhodium and dichloride palladium complexes were found to be cis-chelates with P,N-bidentate ligands. (C) 2000 Published by Elsevier Science S.A.

  DOI：

  10.1016/s0022-328x(00)00373-9

文献信息

• Quincoridine-based aminophosphite ligands and their Rh(I) and Pd(II) complexes
  作者：A.I Polosukhin、K.N Gavrilov、O.G Bondarev、A.V Korostylev、P.V Petrovskii、V.A Davankov

  DOI：10.1016/s0022-328x(00)00373-9

  日期：2000.8

  New chiral P,N-bidentate ligands containing a quincoridine fragment with a configuration-stable N-donating center were obtained. Coordination of the ligands to Rh(I) and Pd(II) atoms was carried out. Chlorocarbonyl rhodium and dichloride palladium complexes were found to be cis-chelates with P,N-bidentate ligands. (C) 2000 Published by Elsevier Science S.A.