4-乙基-1-氮杂双环[2.2.2]辛烷 | 45732-65-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 奎宁环
• 中文名称: 4-乙基-1-氮杂双环[2.2.2]辛烷
• 英文名称: 4-Aethyl-chinuclidin
• 英文别名: 4-Ethyl-chinuclidin；4-ethyl-1-aza-bicyclo[2.2.2]octane；4-Ethylquinuclidine；4-ethyl-1-azabicyclo[2.2.2]octane
• CAS: 45732-65-8
• 化学式: C₉H₁₇N
• 分子量: 139.241
• InChiKey: ZLPCABMSTVWUGB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2933990090

文献信息

• N-aryl pyrazole compounds, compositions, and methods for their use
  申请人：Ogawa Yasuyuki

  公开号：US20080153778A1

  公开（公告）日：2008-06-26

  Compounds having formula I: where A 1 , A 2 , L, V, W, R 1 , R 2 , R 3 , R 4 and R 5 are as described herein, compositions thereof, and their use for the treatment or prevention of type 2 diabetes and type 2 diabetes-related conditions are provided herein.

  本文提供化学式为I的化合物，其中A1、A2、L、V、W、R1、R2、R3、R4和R5如本文所述，以及其组合物，并用于治疗或预防2型糖尿病和2型糖尿病相关疾病。
• N-ARYL PYRAZOLE COMPOUNDS FOR USE AGAINST DIABETES
  申请人：Amgen Inc.

  公开号：EP2079728B1

  公开（公告）日：2013-09-25
• QUINUCLIDIN-4-YLMETHYL 1H-INDOLE-3-CARBOXYLATE DERIVATIVES AS ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
  申请人：COMENTIS, INC.

  公开号：EP2217597B1

  公开（公告）日：2011-03-30
• COMPOSITIONS OF CHK1 INHIBITORS AND CYCLODEXTRIN
  申请人：Wisdom Wendy A.

  公开号：US20100022512A1

  公开（公告）日：2010-01-28

  Compositions containing at least one Chk1 inhibitor and at lease one cyclodextrin are disclosed. Also disclosed are methods of treating a cancer or potentiating a cancer treatment with a composition comprising at least one Chk1 inhibitor and at least one cyclodextrin.
• THERAPEUTIC COMPOSITIONS AND RELATED METHODS OF USE
  申请人：Kiesman William F.

  公开号：US20100063071A1

  公开（公告）日：2010-03-11

  Compositions and dosage forms including adenosine receptor antagonists such as 3-[4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-bicyclo[2.2.2]oct-1-yl]-propionic acid and methods of using the same are described herein.

表征谱图