trigoneoside VIIIb

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: trigoneoside VIIIb
• 英文别名: (2S,3R,4R,5R,6S)-2-[(2R,3R,4S,5S,6R)-5-[(2S,3R,4S,5R,6R)-4-[(2S,3R,4R,5S,6R)-3,4-dihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-5-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)-2-[[(1R,2S,4S,7S,8R,9S,12S,13S,16S,18S)-6-hydroxy-7,9,13-trimethyl-6-[(3R)-3-methyl-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybutyl]-5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosan-16-yl]oxy]oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
• 化学式: C₆₈H₁₁₄O₃₇
• 分子量: 1523.63
• InChiKey: PDOPUWAUAHTOHR-DMGTVJNUSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -6.2
• 重原子数：
  105
• 可旋转键数：
  23
• 环数：
  12.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  584
• 氢给体数：
  22
• 氢受体数：
  37

反应信息

• 作为反应物：
  描述：

  甲醇 、 trigoneoside VIIIb 在 盐酸 作用下， 反应 2.5h， 以51.5%的产率得到剑麻皂素
  参考文献：
  名称：

  Medicinal Foodstuffs. VIII. Fenugreek Seed.(2) : Structures of Six New Furostanol Saponins, Trigoneosides IVa, Va, Vb, VI, VIIb, and VIIIb, from the Seeds of Indian Trigonella foenum-graecum L.

  摘要：

  Following the characterization of trigoneosides Ia, Ib, IIa, IIb, IIIa, and IIIb, seven new steroidal saponins called trigoneosides IVa, Va, Vb, VI, VIIb, VIIIb, and IX were isolated from a medicinal foodstuff fenugreek seed, the seeds of Trigonella foenum-graecum L. (Leguminosae) originating from India. The structures of trigoneosides IVa, Va, Vb, VI, VIIb, and VIIIb were elucidated on the basis of chemical and physicochemical evidence.

  DOI：

  10.3987/com-97-s(n)52

文献信息

• Medicinal Foodstuffs. VIII. Fenugreek Seed.(2) : Structures of Six New Furostanol Saponins, Trigoneosides IVa, Va, Vb, VI, VIIb, and VIIIb, from the Seeds of Indian Trigonella foenum-graecum L.
  作者：Masayuki Yoshikawa、Toshiyuki Murakami、Hajime Komatsu、Johji Yamahara、Hisashi Matsuda

  DOI：10.3987/com-97-s(n)52

  日期：——

  Following the characterization of trigoneosides Ia, Ib, IIa, IIb, IIIa, and IIIb, seven new steroidal saponins called trigoneosides IVa, Va, Vb, VI, VIIb, VIIIb, and IX were isolated from a medicinal foodstuff fenugreek seed, the seeds of Trigonella foenum-graecum L. (Leguminosae) originating from India. The structures of trigoneosides IVa, Va, Vb, VI, VIIb, and VIIIb were elucidated on the basis of chemical and physicochemical evidence.