methyl 2,4-bis(1-naphthyl)-6-(methylthio)benzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: methyl 2,4-bis(1-naphthyl)-6-(methylthio)benzoate
• 英文别名: Methyl 2-methylsulfanyl-4,6-dinaphthalen-1-ylbenzoate
• 化学式: C₂₉H₂₂O₂S
• 分子量: 434.558
• InChiKey: YWYNKEXZGGVYSV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8
• 重原子数：
  32
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  51.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-萘乙酮 、 methyl 4-(methylthio)-6-(naphthalen-1-yl)-2-oxo-2H-pyran-3-carboxylate 在 氢氧化钾 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 33.0h， 以68%的产率得到methyl 2,4-bis(1-naphthyl)-6-(methylthio)benzoate
  参考文献：
  名称：

  An Innovative Synthesis of Unsymmetrical Tetrahydrobinaphthyls, Binaphthyls with a Phenyl Spacer, and Tetrahydroazabinaphthyls through Ring Transformation Reactions of 6-Naphthyl-2-pyrones

  摘要：

  An innovative approach to the synthesis of unsymmetrical tetrahydrobinaphthyls (3), binaphthyls with a phenyl spacer (5), and tetrahydroazabinaphthyls (7) is delineated and illustrated from functionalized 3-(carbomethoxy)-4-(methylthio)-6-naphthyl-2H-pyran-2-one through base-catalyzed ring transformation reactions.

  DOI：

  10.1021/jo9821123

文献信息

• An Innovative Synthesis of Unsymmetrical Tetrahydrobinaphthyls, Binaphthyls with a Phenyl Spacer, and Tetrahydroazabinaphthyls through Ring Transformation Reactions of 6-Naphthyl-2-pyrones
  作者：Vishnu Ji Ram、Atul Goel

  DOI：10.1021/jo9821123

  日期：1999.4.1

  An innovative approach to the synthesis of unsymmetrical tetrahydrobinaphthyls (3), binaphthyls with a phenyl spacer (5), and tetrahydroazabinaphthyls (7) is delineated and illustrated from functionalized 3-(carbomethoxy)-4-(methylthio)-6-naphthyl-2H-pyran-2-one through base-catalyzed ring transformation reactions.