2-(bis(pentylthio)methyl)phenol

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-(bis(pentylthio)methyl)phenol
• 英文别名: 2-[Bis(pentylsulfanyl)methyl]phenol；2-[bis(pentylsulfanyl)methyl]phenol
• 化学式: C₁₇H₂₈OS₂
• 分子量: 312.541
• InChiKey: KIMCWKDPDPRYMU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.4
• 重原子数：
  20
• 可旋转键数：
  11
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  70.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-戊硫醇 、 水杨醛 在 graphene oxide 作用下， 以 neat (no solvent) 为溶剂， 反应 8.0h， 以89%的产率得到2-(bis(pentylthio)methyl)phenol
  参考文献：
  名称：

  Graphene oxide (GO)-catalyzed chemoselective thioacetalization of aldehydes under solvent-free conditions

  摘要：

  An efficient method for the synthesis of open chain, cyclic, and unsymmetrical dithioacetals from aryl/hetero-aryl/aliphatic aldehydes is described. The reaction is performed using graphene oxide (GO) as the catalyst under solvent-free and aerobic conditions. High chemoselectivity is observed in the reaction as aryl/alkyl ketones do not give thioketals under the condition. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.10.043

文献信息

• Graphene oxide (GO)-catalyzed chemoselective thioacetalization of aldehydes under solvent-free conditions
  作者：Babli Roy、Debasish Sengupta、Basudeb Basu

  DOI：10.1016/j.tetlet.2014.10.043

  日期：2014.11

  An efficient method for the synthesis of open chain, cyclic, and unsymmetrical dithioacetals from aryl/hetero-aryl/aliphatic aldehydes is described. The reaction is performed using graphene oxide (GO) as the catalyst under solvent-free and aerobic conditions. High chemoselectivity is observed in the reaction as aryl/alkyl ketones do not give thioketals under the condition. (C) 2014 Elsevier Ltd. All rights reserved.