1,6-bis(1,2,3,4-tetrahydronaphthalen-1-yloxy)hexa-2,4-diyne

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 英文名称: 1,6-bis(1,2,3,4-tetrahydronaphthalen-1-yloxy)hexa-2,4-diyne
• 化学式: C₂₆H₂₆O₂
• 分子量: 370.491
• InChiKey: UKZWQKVBTZWNFL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.18
• 重原子数：
  28.0
• 可旋转键数：
  4.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  18.46
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  1,2,3,4-四氢-1-萘酚 在 copper(l) iodide 、 ethyl 2,2-dibromoacetoacetate 、 sodium hydride 、 三乙胺 作用下， 以 二氯甲烷 、 N,N-二甲基甲酰胺 、 mineral oil 为溶剂， 反应 30.0h， 生成 1,6-bis(1,2,3,4-tetrahydronaphthalen-1-yloxy)hexa-2,4-diyne
  参考文献：
  名称：

  A mild CuI-catalyzed Glaser-type homo-coupling reaction using α,α-dibromo-β-dicarbonyl compounds as oxidants

  摘要：

  Exploration of alpha,alpha-dibromo-beta-dicarbonyl compounds as novel organic oxidants for the mild Cu(I)-catalyzed Glaser-type homo-coupling reaction has been achieved, which provides an alternatively efficient pathway for the construction of 1,3-conjugated structures. In addition, the mechanism of this reaction was investigated. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2013.11.076

文献信息

• A mild CuI-catalyzed Glaser-type homo-coupling reaction using α,α-dibromo-β-dicarbonyl compounds as oxidants
  作者：Xiaohui Fan、Na Li、Tong Shen、Xiao-Meng Cui、Hao Lv、Hong-Bo Zhu、Yong-Hong Guan

  DOI：10.1016/j.tet.2013.11.076

  日期：2014.1

  Exploration of alpha,alpha-dibromo-beta-dicarbonyl compounds as novel organic oxidants for the mild Cu(I)-catalyzed Glaser-type homo-coupling reaction has been achieved, which provides an alternatively efficient pathway for the construction of 1,3-conjugated structures. In addition, the mechanism of this reaction was investigated. (C) 2013 Elsevier Ltd. All rights reserved.