尿苷,5'-[[[2-[(1-羰基癸基)氨基]-3-苯基丙氧基]羰基]氨基磺酸酯](9CI) | 149970-64-9

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷
• 中文名称: 尿苷,5'-[[[2-[(1-羰基癸基)氨基]-3-苯基丙氧基]羰基]氨基磺酸酯](9CI)
• 中文别名: [2-(癸酰氨基)-3-苯基丙基]N-[[(2R,3S,4R,5R)-5-(2,4-二氧代嘧啶-1-基)-3,4-二羟基四氢呋喃-2-基]甲氧基磺酰基]氨基甲酸酯
• 英文名称: Uridine, 5'-(((2-((1-oxodecyl)amino)-3-phenylpropoxy)carbonyl)sulfamate)
• 英文别名: [2-(decanoylamino)-3-phenylpropyl] N-[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxysulfonyl]carbamate
• CAS: 149970-64-9；165307-53-9
• 化学式: C₂₉H₄₂N₄O₁₁S
• 分子量: 654.7
• InChiKey: UADKHKLHAYUHAB-UHFDHVSFSA-N

物化性质

• 密度：
  1.346±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  45
• 可旋转键数：
  19
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  218
• 氢给体数：
  5
• 氢受体数：
  11

文献信息

• Obesity small molecules
  申请人：Akron Molecules GmbH

  公开号：EP2633884A1

  公开（公告）日：2013-09-04

  The present invention relates to new therapies to treat obesity and related diseases, as well as for reducing triglyceride levels and body weight.

  本发明涉及治疗肥胖症和相关疾病以及降低甘油三酯水平和体重的新疗法。
• FMO3 inhibitors for treating pain
  申请人：Akron Molecules GmbH

  公开号：EP2674161A1

  公开（公告）日：2013-12-18

  The present invention relates to new therapies to treat pain and related diseases, as well as pharmaceutical compounds for use in said therapies.

  本发明涉及治疗疼痛和相关疾病的新疗法，以及用于上述疗法的药物化合物。
• Obesity Small Molecules
  申请人：Penninger Josef

  公开号：US20130030007A1

  公开（公告）日：2013-01-31

  The present invention relates to new therapies to treat obesity and related diseases, as well as for reducing triglyceride levels and body weight.
• Compounds and Methods for Treating Pain
  申请人：Penninger Josef

  公开号：US20130252924A1

  公开（公告）日：2013-09-26

  The present invention relates to new therapies to treat pain and related diseases, as well as pharmaceutical compounds for use in said therapies.
• COMPOUNDS AND METHODS FOR TREATING PAIN
  申请人：AKRON MOLECULES AG

  公开号：US20140349969A1

  公开（公告）日：2014-11-27

  The present invention relates to new therapies to treat pain and related diseases, as well as pharmaceutical compounds for use in said therapies.