1,1,2,2,3,3,4,4-八氟-1,2,3,4-四氢萘 | 3262-14-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 四氢化萘
• 中文名称: 1,1,2,2,3,3,4,4-八氟-1,2,3,4-四氢萘
• 英文名称: 1,1,2,2,3,3,4,4-octafluoro-1,2,3,4-tetrahydronaphthalene
• 英文别名: 1,1,2,2,3,3,4,4-octafluorotetralin；1,1,2,2,3,3,4,4-Octafluor-tetralin；Benzo-perfluorcyclohexan；1,1,2,2,3,3,4,4-octafluoronaphthalene
• CAS: 3262-14-4
• 化学式: C₁₀H₄F₈
• 分子量: 276.129
• InChiKey: DQBNYIULYVPTCR-UHFFFAOYSA-N

物化性质

• 沸点：
  90 °C(Press: 42 Torr)
• 密度：
  1.516 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  18
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  1,1,2,2,3,3,4,4-八氟-1,2,3,4-四氢萘 在 硫酸 、 三氧化硫 、 硝酸 作用下， 生成 3,3,4,4,5,5,6,6-octafluorocyclohexene-1,2-dicarboxylic acid
  参考文献：
  名称：

  Galushko,A.G. et al., Journal of general chemistry of the USSR, 1967, vol. 37, p. 1903 - 1906

  摘要：

  DOI：
• 作为产物：
  描述：

  在 碘 作用下， 生成 1,1,2,2,3,3,4,4-八氟-1,2,3,4-四氢萘
  参考文献：
  名称：

  Galushko,A.G. et al., Journal of general chemistry of the USSR, 1967, vol. 37, p. 1903 - 1906

  摘要：

  DOI：

文献信息

• [EN] REAGENTS AND METHODS FOR FLUORINATING A SUBSTRATE<br/>[FR] RÉACTIFS ET PROCÉDÉS DE FLUORATION D'UN SUBSTRAT
  申请人：UNIV LEHIGH

  公开号：WO2015006278A1

  公开（公告）日：2015-01-15

  Described herein are perfiuoroalkylated zinc compounds having the structure of Formula (I) or Formula (II), which can be used to · perfluoroalkylate organic, inorganic and organometallic substrates. Methods of making and using these compounds by reacting zinc or a dialkylzinc compound with a perfluoroalkyl dihalide in a solvent such as tetrahydrofuran, dioxane or diglyme, are also described.

  本文描述了具有Formula（I）或Formula（II）结构的全氟烷基化锌化合物，可用于对有机、无机和有机金属底物进行全氟烷基化。还描述了通过在诸如四氢呋喃、二恶英或二甘醚等溶剂中将锌或二烷基锌化合物与全氟烷基二卤代烃反应制备和使用这些化合物的方法。
• Synthetic utility of dizinc reagents derived from 1,4-diiodo- and 1,4-dibromooctafluorobutane
  作者：Peter T. Kaplan、Bo Chen、David A. Vicic

  DOI：10.1016/j.jfluchem.2014.09.023

  日期：2014.12

  A modified procedure to prepare [(MeCN)(2)Zn((CF2)(4))(2)Zn(MeCN)(2)] has been developed that allows for more reproducible yields of novel organofluorines during cross-coupling protocols. Additionally, the related reagent [(diglyme)BrZn-(CF2)(4)-ZnBr(digylme)I has been prepared and was shown to be similarly active for [C4F8] transfer to both organic and inorganic substrates. The di(zinc halide) reagent is operationally simple to prepare using inexpensive and easy to handle zinc metal. (C) 2014 Elsevier B.V. All rights reserved.
• Mild, Safe, and Versatile Reagents for (CF₂)_<i>n</i> Transfer and the Construction of Fluoroalkyl-Containing Rings
  作者：Peter T. Kaplan、Long Xu、Bo Chen、Katherine R. McGarry、Siqi Yu、Huan Wang、David A. Vicic

  DOI：10.1021/om401016k

  日期：2013.12.23

  The preparation of new dizinc reagents [(MeCN)(2)Zn((CF2)(n))(2)Zn(MeCN)(2)] (n = 3, 4, and 6) is reported. We show that the C4 reagent can readily transmetalate nickel to form a mononuclear perfluoronickela-cycle. We also demonstrate that the reagents can be used to prepare novel fluoroorganics containing either perfluoroalkyl ring systems or perfluoroalkyl linked arenes under relatively mild conditions.
• Platonov, V. E.; Malyuta, N. G.; Yakobson, G. G., Journal of Organic Chemistry USSR (English Translation), 1985, vol. 21, # 2, p. 345 - 353
  作者：Platonov, V. E.、Malyuta, N. G.、Yakobson, G. G.

  DOI：——

  日期：——
• MALICHENKO V. F.; KRASNOSHCHEK A. P., DOKL. AN USSR, 1981, B, HO 4, 41-43
  作者：MALICHENKO V. F.、 KRASNOSHCHEK A. P.

  DOI：——

  日期：——