spiro[imidazo[1,2-a]pyridin-2(3H)-one-3,2'-((1,2,5-thiadiazo)[4,5-c]indan)] | 1020268-27-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并吡啶类
• 英文名称: spiro[imidazo[1,2-a]pyridin-2(3H)-one-3,2'-((1,2,5-thiadiazo)[4,5-c]indan)]
• 英文别名: Spiro[5,7-dihydrocyclopenta[f][2,1,3]benzothiadiazole-6,3'-imidazo[1,2-a]pyridine]-2'-one
• CAS: 1020268-27-2
• 化学式: C₁₅H₁₀N₄OS
• 分子量: 294.337
• InChiKey: WBEKRPHCQATXEW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  21
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  86.7
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• METHODS FOR TREATING DELAYING THE PROGRESSION OF ALZHEIMER'S DISEASE WITH HETEROCYCLIC COMPOUNDS
  申请人：Yamaguchi Yoshimasa

  公开号：US20080103158A1

  公开（公告）日：2008-05-01

  Disclosed is an antidepressant, neuroprotectant, amyloid β deposition inhibitor, or age retardant composition containing a heterocyclic compound having the general formula (I):
• METHODS FOR TREATING DEPRESSION, NEURODEGENERATION, INHIBITING AMYLOID BETA DEPOSITION, DELAYING SENESCENCE, AND EXTENDING LIFE SPANS WITH HETEROCYCLIC COMPOUNDS
  申请人：YAMAGUCHI Yoshimasa

  公开号：US20140171452A1

  公开（公告）日：2014-06-19

  Disclosed is an antidepressant, neuroprotectant, amyloid β deposition inhibitor, or age retardant composition containing a heterocyclic compound having the general formula (I):
• US9089561B2
  申请人：——

  公开号：US9089561B2

  公开（公告）日：2015-07-28