愈创木酚磺酸钾半水合物 | 16241-25-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 中文名称: 愈创木酚磺酸钾半水合物
• 英文名称: Sulfogaiacol
• CAS: 16241-25-1
• 化学式: C7H8KO5S
• 分子量: 243.3
• InChiKey: UQLUGIAIXOWYBP-UHFFFAOYSA-N

物化性质

• 熔点：
  231 - 232°C
• 溶解度：
  可溶于甲醇（轻微、加热、超声处理）、水（可溶、加热）

计算性质

• 辛醇/水分配系数(LogP)：
  0.27
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  92.2
• 氢给体数：
  2
• 氢受体数：
  5

安全信息

• 储存条件：
  室温且干燥环境下使用。

文献信息

• [EN] C20-C21 SUBSTITUTED GLUCOCORTICOID RECEPTOR AGONISTS<br/>[FR] AGONISTES DU RÉCEPTEUR DE GLUCOCORTICOÏDE SUBSTITUÉS EN C20-C21
  申请人：SCHERING CORP

  公开号：WO2009085879A2

  公开（公告）日：2009-07-09

  The present invention provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, esters, prodrugs, tautomers, or isomers of said compounds), having general structure (I); wherein L, R1, R2, R3, R4, R5, and R6 are selected independently of each other and as defined herein. The present invention also provides compounds (and salts, solvates, esters, prodrugs, tautomers, and isomers) of Formulas II, III, IV, V, and Vl, as defined herein. Also provided are pharmaceutical compositions, methods of preparing, and methods of using such compounds in the treatment and prophylaxis of a wide range of immune, autoimmune, and inflammatory diseases and conditions.

  本发明提供了具有一般结构（I）的化合物，以及该化合物的药用盐、溶剂合物、酯、前药、互变体或异构体（包括L、R1、R2、R3、R4、R5和R6在内独立选择的定义）。本发明还提供了根据本文所定义的化合物（和盐、溶剂合物、酯、前药、互变体和异构体）的II、III、IV、V和VI式化合物。还提供了药物组合物、制备方法以及利用这些化合物在治疗和预防各种免疫、自身免疫和炎症性疾病和症状中的方法。
• MODIFIED HYDROPHILIC ACRYLIC RESIN FILM
  申请人：Mitsui Chemicals, Inc.

  公开号：EP2860215A1

  公开（公告）日：2015-04-15

  [Problem] To provide hydrophilic modified acrylic resin films which exhibit excellent antifogging properties and antifouling properties and high transparency. [Solution] A modified acrylic resin film of the invention is obtained by treating a surface of an acrylic resin film having anionic hydrophilic groups with a compound (A), the acrylic resin film being such that the concentration of the anionic hydrophilic groups on the surface is higher than the concentration of the anionic hydrophilic groups at a depth half the film thickness from the surface of the acrylic resin film, the compound (A) having in the molecule thereof one or more anionic hydrophilic groups and one or more groups selected from groups having a polymerizable carbon-carbon double bond, amino groups, mercapto groups and hydroxyl groups.

  问题 提供亲水性改性丙烯酸树脂薄膜，使其具有优异的防雾性能和防污性能，以及高透明度。 [解决方案］ 本发明的一种改性丙烯酸树脂薄膜是通过用一种化合物（A）处理具有阴离子亲水基团的丙烯酸树脂薄膜的表面而获得的，该丙烯酸树脂薄膜的表面上的阴离子亲水基团的浓度高于从丙烯酸树脂薄膜表面算起的一半膜厚深度处的阴离子亲水基团的浓度、化合物 (A) 分子中具有一个或多个阴离子亲水基团和一个或多个选自具有可聚合碳碳双键的基团、氨基、巯基和羟基的基团。
• HYDROPHILIC SINGLE-LAYER FILM HAVING OPTICAL FUNCTIONALITY, AND LAMINATE THEREOF
  申请人：Mitsui Chemicals, Inc.

  公开号：EP3270192A1

  公开（公告）日：2018-01-17

  In the present invention, there is provided a hydrophilic monolayer film that is excellent in antifogging properties, antifouling properties, the durability of antifogging properties and antifouling properties, and smoothness and that has an antireflective function or a surface structure that serves as a polarizer. There is also provided a method for easily producing such a monolayer film. The monolayer film that is to be produced has a surface structure with multiple protrusions and depressions. The distance between the peaks of adjoining protrusions among such multiple protrusions is in the range of 1 nm to 800 nm. The monolayer film is formed of a crosslinked resin produced by curing of a polymerizable composition that contains a compound having a specific hydrophilic group and a functional group with a polymerizable carbon-carbon double bond and a compound having two or more (meth)acryloyl groups. A gradient of the concentration of hydrophilic groups (Sa2/Da2) in the monolayer film is not less than 1.1 wherein Sa is the concentration of at least one type of hydrophilic groups selected from anionic hydrophilic groups, cationic hydrophilic groups, and a hydroxyl group at the top layer, and Da is the depth concentration of the hydrophilic groups at 1/2 of the thickness of the monolayer film.

  本发明提供了一种亲水单层膜，它在防雾性能、防污性能、防雾性能和防污性能的耐久性以及平滑性方面都非常出色，并且具有防反射功能或可用作偏振器的表面结构。此外，还提供了一种易于生产这种单层薄膜的方法。要生产的单层薄膜具有多突起和凹陷的表面结构。在这些多个突起中，相邻突起的峰值之间的距离在 1 纳米到 800 纳米之间。单层膜由可聚合组合物固化产生的交联树脂形成，该组合物包含具有特定亲水基团和具有可聚合碳碳双键的官能团的化合物以及具有两个或两个以上（甲基）丙烯酰基的化合物。单层膜中亲水基团的浓度梯度(Sa2/Da2)不小于 1.1，其中 Sa 是选自阴离子亲水基团、阳离子亲水基团和羟基的至少一种亲水基团在顶层的浓度，Da 是亲水基团在单层膜厚度 1/2 处的深度浓度。
• Antimicrobial agents
  申请人：——

  公开号：US20030055007A1

  公开（公告）日：2003-03-20

  Purposes To confirm the efficacy from the chemical substances found in industrial products, which can be supplied with relative stability and continuance, do not produce many side effects, prove that they attain desirable antimicrobial activity and to then make them accepted antimicrobial agents. Composition Antimicrobial agents comprising of one or more active constituents having antimicrobial activity, which are selected from guaiacol, lignin sulfonic acid, 2,6-dimethoxyphenol, 3,5-dimethoxyphenol, lignosulfonic acid sodium salt, lignosulfonic acid sodium salt acetate, lignin organosolv propionate, 4-benzyloxyguaiacylglycerol-&bgr;-guaiacylether and syringaldehyde. Effectiveness Differing from natural products and being antimicrobial agents comprising of industrial products, they are stable from a quantitative and quality point of view, safe and inexpensive and antiviral as well as antibacterial activity can be attained.

  目的 从工业产品中发现的化学物质中确认其功效，这些物质可以相对稳定地持续供应，不会产生很多副作用，证明它们具有理想的抗菌活性，然后使其成为公认的抗菌剂。 成分 由一种或多种具有抗菌活性的活性成分组成的抗菌剂，这些活性成分选自愈创木酚、木质素磺酸、2,6-二甲氧基苯酚、3,5-二甲氧基苯酚、木质素磺酸钠盐、木质素磺酸钠醋酸盐、木质素有机溶剂丙酸盐、4-苄氧基愈创木甘油-&bgr；-愈创木醚和丁香醛。 功效 与天然产品不同，作为由工业产品组成的抗菌剂，它们在数量和质量上都比较稳定，安全且价格低廉，可以达到抗病毒和抗菌的活性。
• Pharmaceutical formulations
  申请人：Lithgow L. Theodore

  公开号：US20060030550A1

  公开（公告）日：2006-02-09

  Disclosed are medicaments containing, separately or together, (A) Pleconaril or a pharmaceutically acceptable salt thereof and (B) a pharmaceutically active agent for simultaneous, sequential or separate administration in the treatment of a viral infection and/or other disease states and the symptoms associated therewith.

  所公开的是分别或共同含有(A) Pleconaril 或其药学上可接受的盐和(B) 一种药学活性剂的药物，用于同时、连续或单独给药，以治疗病毒感染和/或其他疾病状态及其相关症状。