1,2-二(10,12-二十三碳二炔酰基)磷脂酰胆碱 | 76078-28-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 中文名称: 1,2-二(10,12-二十三碳二炔酰基)磷脂酰胆碱
• 英文名称: 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphocholine
• 英文别名: 1,2-bis(tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine；1,2-Bis(10,12-tricosadiynoyl)phosphatidylcholine；[(2R)-2,3-di(tricosa-10,12-diynoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
• CAS: 76078-28-9
• 化学式: C₅₄H₉₂NO₈P
• 分子量: 914.3
• InChiKey: IDBJTPGHAMAEMV-OIVUAWODSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  17.3
• 重原子数：
  64
• 可旋转键数：
  46
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  111
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  Docosa-8,10-diynoic acid (3-{2-[2-(2-aminooxy-acetylamino)-ethoxy]-ethoxy}-propyl)-amide 、 1,2-二(10,12-二十三碳二炔酰基)磷脂酰胆碱 生成 polymer; monomer(s): N-{3-[2-(2-{[(aminooxy)acetyl]amino}ethoxy)ethoxy]propyl}docosa-8,10-diynamide; 1,2-bis-(tricosa-10,12-diynoyl)-sn-glycero-3-phosphocholine
  参考文献：
  名称：

  摘要：

  DOI：

文献信息

• Targeted multivalent macromolecules
  申请人：TARGESOME, INC.

  公开号：US20030129223A1

  公开（公告）日：2003-07-10

  Targeted therapeutic agents, comprising a linking carrier, a therapeutic entity associated with the linking carrier, and at least one targeting entity are provided, as well as methods for their preparation and use.

  靶向治疗剂，包括一个连接载体，与连接载体相关联的治疗实体，以及至少一个靶向实体，以及它们的制备和使用方法。
• ACTIVATABLE NANOPROBES FOR INTRACELLULAR DRUG DELIVERY
  申请人：Santra Swadeshmukul

  公开号：US20130006007A1

  公开（公告）日：2013-01-03

  An activatable nanoprobe is provided having a core component and an active agent associated with the core component via a bond configured to be cleaved upon exposure to an endogenous compound.

  提供了一种可激活纳米探针，具有一个核心组件和一个活性剂，通过一种键与核心组件相关联，该键被配置为在暴露于内源性化合物时被裂解。
• End-to-end joining of nanotubes
  申请人：Russell Alan J.

  公开号：US20100137541A1

  公开（公告）日：2010-06-03

  A method for joining nanotubes end-to-end, includes contacting the nanotubes with a joining fluid. The joining fluid has at least one property that is different from at least one property associated with ends of the nanotubes. In one embodiment, the method further includes contacting the nanotubes with a first, treating fluid and removing the bulk first fluid before the nanotubes are contacted with the joining fluid. The joining fluid is immiscible in the treating fluid to effect end-to-end joining of the nanotubes.

  一种将纳米管端对端连接的方法，包括将纳米管与连接液接触。连接液具有至少一种与纳米管端相关的属性不同。在一种实施例中，该方法还包括将纳米管与第一处理液接触，并在纳米管与连接液接触之前去除大部分第一液体。连接液与处理液不相溶，以实现纳米管的端对端连接。
• Methods for manufacturing supported lipid membranes
  申请人：Universität für Bodenkultur Wien

  公开号：EP1777520A1

  公开（公告）日：2007-04-25

  Method for the manufacturing of a supported lipid membrane comprising the steps: - providing a substrate, covered at least in part with a layer comprising proteins, glycoproteins, polypeptides and/or peptides, - contacting and incubating said substrate with a solution comprising bicelles, which comprise at least one short chain and at least one long chain phospholipid and/or at least one detergent, thereby producing a supported lipid membrane, and - optionally removing the lipid membrane formed on the substrate from said substrate.

  制造支撑脂膜的方法，包括以下步骤 - 提供至少部分覆盖有蛋白质、糖蛋白、多肽和/或肽层的基底、 - 将所述基质与含有双胞的溶液接触并培养，双胞包括至少一种短链磷脂和至少一种长链磷脂和/或至少一种洗涤剂，从而产生支撑脂膜，以及 - 将在基底上形成的脂膜从基底上移除。
• FUNCTIONAL POLYMER GEL CONTAINING ORGANIC NANOTUBES AND METHOD FOR PRODUCING SAME
  申请人：Seed Co., Ltd.

  公开号：EP3156076A1

  公开（公告）日：2017-04-19

  The purpose of the present invention is to provide: a functional polymer gel which is able to be practically used as an ocular lens having excellent transparency and mechanical strength by uniformly dispersing organic nanotubes in a polymer gel without the formation of agglomerates of the organic nanotubes in the case where the organic nanotubes are complexed into the polymer gel; and a method for producing this functional polymer gel. The above-mentioned purpose is achieved by: a functional polymer gel which is characterized by containing organic nanotubes and having a light transmittance of 80% or more; and a method for producing this functional polymer gel.

  本发明的目的是提供：一种功能性聚合物凝胶，通过将有机纳米管均匀分散在聚合物凝胶中，在有机纳米管络合到聚合物凝胶中的情况下，有机纳米管不会形成团块，从而能够实际用作具有优异透明度和机械强度的眼透镜；以及生产这种功能性聚合物凝胶的方法。上述目的是通过以下方法实现的：一种功能性聚合物凝胶，其特征在于含有有机纳米管，且透光率大于等于 80%；以及一种生产这种功能性聚合物凝胶的方法。