1,2-二肉豆蔻酰基-sn-甘油-3-磷酸-L-丝氨酸(钠盐)

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 中文名称: 1,2-二肉豆蔻酰基-sn-甘油-3-磷酸-L-丝氨酸(钠盐)
• 中文别名: 1,2-二十四烷酰基-sn-甘油-3-磷酸-L-丝氨酸（钠盐）；DMPS;PS(14:0/14:0)
• 英文名称: sodium;(2S)-2-amino-3-[[(2R)-2,3-di(tetradecanoyloxy)propoxy]-hydroxyphosphoryl]oxypropanoate
• 化学式: C34H65NNaO10P
• 分子量: 701.8
• InChiKey: QSHQBWBFNCFHLO-MFABWLECSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  2.71
• 重原子数：
  47
• 可旋转键数：
  35
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  179
• 氢给体数：
  1
• 氢受体数：
  10

文献信息

• NOVEL FORMULATION OF PEGYLATED-LIPOSOME ENCAPSULATED GLYCOPEPTIDE ANTIBIOTICS
  申请人：Western University Of Health Sciences

  公开号：EP2582358A1

  公开（公告）日：2013-04-24
• TERNARY MIXTURE FORMULATIONS
  申请人：Western University Of Health Sciences

  公开号：EP2632437A2

  公开（公告）日：2013-09-04
• EP3799888A1
  申请人：——

  公开号：EP3799888A1

  公开（公告）日：2021-04-07
• Regional delivery of therapeutic agents for the treatment of vascular diseases
  申请人：Pacetti Stephen D.

  公开号：US20080146489A1

  公开（公告）日：2008-06-19

  The present invention relates to the regional delivery of therapeutic agents for the treatment of vascular diseases wherein regional delivery refers to delivery of a therapeutically effective amount of the therapeutic agent to an area of the vessel that includes not only afflicted tissue but non-afflicted tissue at the periphery of the afflicted tissue as well.
• Drug Delivery System and Method of Treatment of Vascular Diseases Using Photodynamic Therapy
  申请人：Hossainy Syed

  公开号：US20100331819A1

  公开（公告）日：2010-12-30

  This invention relates to photodynamic therapy (PDT), more specifically PDT for atherosclerotic plaque via delivering PDT-loaded nanoparticles such as liposomes, polymersomes, micelles and polymeric nanoparticles into the diseased vascular tissue. This invention provides method and formulations for delivering multiple drugs and delivering drugs to specific targeted site.