1,3-二(2-甲基氮丙啶-1-基)丙-2-醇 | 1690-48-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 1,3-二(2-甲基氮丙啶-1-基)丙-2-醇
• 英文名称: 1,3-Bis(2-methylaziridin-1-yl)propan-2-ol
• CAS: 1690-48-8
• 化学式: C₉H₁₈N₂O
• 分子量: 170.25
• InChiKey: SRJAHAZGKBBXMG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26.2
• 氢给体数：
  1
• 氢受体数：
  3

安全信息

• 海关编码：
  2933990090

文献信息

• Cross-linked hyaluronate compounds
  申请人：Gianolio A. Diego

  公开号：US20050222081A1

  公开（公告）日：2005-10-06

  There is disclosed a cross-linked hyaluronate compound obtained by reacting a sodium hyaluronate compound with a polfunctional aziridine compound as a cross-linking agent. The polyfunctional aziridine compound was added to hyaluronan of various molecular weights in an equivalent ratio of HA/AZ of 1:1 to 1:10, preferably, 1:3 to 1:10, more preferably, 1:3 to 1:5; most preferably 1:4 to 1:5. The polymeric hydrogel compounds obtained are useful to prevent the formation of post-operative adhesions, designing tissue engineering applications, and the like.

  披露了一种交联透明质酸化合物，其通过将钠透明质酸化合物与多官能环氧乙烷化合物作为交联剂反应而获得。将多官能环氧乙烷化合物添加到不同分子量的透明质酸钠中，其HA/AZ的当量比为1:1至1:10，优选为1:3至1:10，更优选为1:3至1:5；最优选为1:4至1:5。所获得的聚合物水凝胶化合物可用于预防术后粘连的形成，设计组织工程应用等。
• Aziridine compounds and their use in medical devices
  申请人：Gianolio A. Diego

  公开号：US20050249953A1

  公开（公告）日：2005-11-10

  There are disclosed novel uses of aziridine compounds. The aziridine compounds can be formed into films by plasma deposition on a wide variety of substrates. The films prevent biofouling, impart biocompatible or antithrombotic properties, and can immobilize therapeutic and pharmaceutical agents to provide a drug delivery system.

  已公开氮丙啶化合物的新用途。氮丙啶化合物可通过等离子沉积在各种基底上形成薄膜。这些薄膜可防止生物污染，具有生物相容性或抗血栓性能，并可固定治疗剂和药剂，提供药物输送系统。
• US7387836B2
  申请人：——

  公开号：US7387836B2

  公开（公告）日：2008-06-17
• [EN] CROSS-LINKED HYALURONATE COMPOUNDS<br/>[FR] COMPOSES DE HYALURONATE RETICULE
  申请人：GENZYME CORP

  公开号：WO2003089476A1

  公开（公告）日：2003-10-30

  There is disclosed a cross-linked hyaluronate compound obtained by reacting a sodium hyaluronate compound with a polyfunctional aziridine compound as a cross-linking agent. The polyfunctional aziridine compound was added to hyaluronan of various molecular weights in an equivalent ratio of HA/AZ of 1:1 to 1:10, preferably, 1:3 to 1:10, more preferably, 1:3 to 1:5; most preferably 1:4 to 1:5.. The polymeric hydrogel compounds obtained are useful to prevent the formation of post-operative adhesions, designing tissue engineering applications, and the like.