抗坏血酸2-硫酸盐 | 37627-95-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢呋喃
• 中文名称: 抗坏血酸2-硫酸盐
• 英文名称: Ascorbic acid 2-sulfate
• 英文别名: [(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-5-oxo-2H-furan-4-yl] hydrogen sulfate
• CAS: 37627-95-5
• 化学式: C₆H₈O₉S
• 分子量: 256.19
• InChiKey: XDBMXUKHMOFBPJ-ZAFYKAAXSA-N

物化性质

• 密度：
  2.07±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.2
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  159
• 氢给体数：
  4
• 氢受体数：
  9

文献信息

• NOVEL ASCORBIC ACID COMPOUNDS, METHODS OF SYNTHESIS AND APPLICATION USE THEREOF
  申请人：ROOMI WAHEED M

  公开号：US20080188553A1

  公开（公告）日：2008-08-07

  A composition of L-ascorbic acid derivatives is described comprising L-ascorbic acid and lysine or lysine moieties, wherein L-ascorbic acid is covalently bound to the lysine or lysine moieties. The composition so described is used to prevent the degradation of extracellular matrix, stabilize connective tissue, is used to as an antioxidant, and is used for treating damage to skin comprising applying the topical composition to the skin.

  描述了一种由L-抗坏血酸衍生物组成的化合物，包括L-抗坏血酸和赖氨酸或赖氨酸基团，其中L-抗坏血酸与赖氨酸或赖氨酸基团共价结合。所述的这种化合物用于防止细胞外基质的降解，稳定结缔组织，作为抗氧化剂使用，并用于治疗皮肤损伤，包括将局部组合物涂抹在皮肤上。
• Novel ascorbic acid compounds, methods of synthesis and application use thereof
  申请人：——

  公开号：US20030119753A1

  公开（公告）日：2003-06-26

  A composition of L-ascorbic acid derivatives is described comprising L-ascorbic acid and lysine or lysine moieties, wherein L-ascorbic acid is covalently bound to the lysine or lysine moieties. The composition so described is used to prevent the degradation of extracellular matrix, stabilize connective tissue, is used to as an antioxident, and is used for treating damage to skin comprising applying the topical composition to the skin.

  本文描述了一种由L-抗坏血酸衍生物组成的组合物，包括L-抗坏血酸和赖氨酸或赖氨酸基团，其中L-抗坏血酸与赖氨酸或赖氨酸基团共价结合。所述的组合物用于预防细胞外基质的降解，稳定结缔组织，作为抗氧化剂使用，并用于治疗皮肤损伤，包括将局部组合物涂抹于皮肤上。
• [EN] LINEAR AND CYCLIC SILOXANES AND COSMETIC COMPOSITIONS MADE THEREOF<br/>[FR] SILOXANES LINÉAIRES ET CYCLIQUES ET COMPOSITIONS COSMÉTIQUES PRÉPARÉES À PARTIR DE CES DERNIERS
  申请人：DOW CORNING TORAY CO LTD

  公开号：WO2011068250A1

  公开（公告）日：2011-06-09

  The present invention relates to a novel organopolysiloxane having a specified structure and a cosmetic containing the aforementioned organopolysiloxane. The novel organopolysiloxane according to the present invention is volatile, possesses stability at low temperature, provides superior glossiness, and has a superior property with respect to miscibility with a UV- ray absorber, and which is useful as a replacement of octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, or methyltrimethicone. The cosmetic according to the present invention can provide superior feeling to the touch during use and a superior outer appearance. Furthermore, a degree of freedom in blending various components such as UV-ray absorbers into the cosmetic according to the present invention is increased.

  本发明涉及一种具有特定结构的新型有机硅聚合物和含有上述有机硅聚合物的化妆品。根据本发明的新型有机硅聚合物具有挥发性，在低温下具有稳定性，提供出色的光泽度，并具有与紫外线吸收剂混溶的优越性能，可用作八甲基环四硅氧烷、十甲基环五硅氧烷或甲基三甲基硅氧烷的替代品。根据本发明的化妆品在使用时可以提供出色的触感和优越的外观。此外，根据本发明的化妆品可以增加混合各种成分，如紫外线吸收剂的自由度。
• TOPICAL AGENT FOR DERMATOLOGICAL USE
  申请人：Nakayama Hiroki

  公开号：US20110014141A1

  公开（公告）日：2011-01-20

  The objective of the present invention was to enhance the skin whitening effects and blackening prevention effects and supply safe and stable topical agents for dermatological use. For that purpose 4-Hydroxyphenyl-α-D-glucopyranoside was combined with auxiliary agents such as ascorbic acid and its derivatives, crude drugs and its extracts, hydroxycarboxylic acid and its salts, oil soluble glycyrrhiza extract, gentian extract, phenol derivatives and their salts, placenta extract, kojic acid and its derivatives, glucosamine and its derivatives, azelaic acid and its derivatives, retinol and its derivatives, pyridoxin and its derivatives, tocopherol and its derivatives, chitosan and its decomposition products, caffeic acid derivatives, hydroxycinnamate and its derivatives, Umbelliferae plant extracts, mycelial cultures and their extracts, plant leaves and their extracts.

  本发明的目的是增强皮肤美白效果和黑色素生成的预防效果，并提供安全稳定的用于皮肤科的局部制剂。为此，4-羟基苯基-α-D-葡萄糖苷与辅助剂如抗坏血酸及其衍生物、天然药物及其提取物、羟基羧酸及其盐、油溶性甘草提取物、龙胆提取物、酚类衍生物及其盐、胎盘提取物、曲酸及其衍生物、葡萄糖胺及其衍生物、癸二酸及其衍生物、视黄醇及其衍生物、吡哆醇及其衍生物、生育酚及其衍生物、壳聚糖及其分解产物、咖啡酸衍生物、羟基肉桂酸及其衍生物、伞形科植物提取物、菌丝培养物及其提取物、植物叶片及其提取物相结合。
• Compositions for topical use having melanin synthesis-inhibiting activity
  申请人：Sansho Seiyaku Co., Ltd.

  公开号：EP0308918A1

  公开（公告）日：1989-03-29

  Compositions for topical use having melanin synthesis-inhibiting activity comprising kojic acid or its esters and vitamin C or its derivatives. The compositions have excellent human skin-whitening effect and anti-suntan effect.

  具有黑色素合成抑制活性的外用组合物，由曲酸或其酯类和维生素 C 或其衍生物组成。这些复合物具有极佳的人体皮肤美白效果和抗褐斑效果。