1,4-二氯庚烷 | 6223-76-3

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氯化物
• 中文名称: 1,4-二氯庚烷
• 英文名称: 1,4-Dichloroheptane
• CAS: 6223-76-3
• 化学式: C₇H₁₄Cl₂
• mdl: MFCD19233788
• 分子量: 169.094
• InChiKey: MAHAWVMUURHVNO-UHFFFAOYSA-N

物化性质

• 熔点：
  23.5°C (estimate)
• 沸点：
  198.96°C (estimate)
• 密度：
  1.0554 (estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 海关编码：
  2903199000

反应信息

• 作为产物：
  描述：

  1-氯庚烷 在 1-氯哌啶 、 偶氮二异丁腈 作用下， 以 三氟乙酸 为溶剂， 生成 1,2-二氯庚烷 、 1,7-二氯庚烷 、 1,3-dichloro-heptane 、 1,6-二氯庚烷 、 1,4-二氯庚烷 、 1,5-二氯庚烷
  参考文献：
  名称：

  Dneprovskii, A. S.; Mil'tsov, S. A.; Arbuzov, P. V., Journal of Organic Chemistry USSR (English Translation), 1988, vol. 24, # 10, p. 1826 - 1835

  摘要：

  DOI：

文献信息

• [EN] INDAZOLE DERIVATIVES USEFUL AS CB-1 INVERSE AGONISTS<br/>[FR] DÉRIVÉS D'INDAZOLE À UTILISER EN TANT QU'AGONISTES INVERSES DE CB-1
  申请人：JANSSEN PHARMACEUTICA NV

  公开号：WO2017034872A1

  公开（公告）日：2017-03-02

  The present invention is directed to indazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions mediated by the CB-1 receptor; more particularly, use in the treatment of disorders and conditions responsive to inverse agonism of the CB-1 receptor. More particularly, the compounds of the present invention are useful in the treatment of metabolic disorders.

  本发明涉及吲唑衍生物，含有它们的药物组合物以及它们在治疗由CB-1受体介导的疾病和症状中的应用；更具体地，用于治疗对CB-1受体的反向激动作用敏感的疾病和症状。更具体地说，本发明的化合物在治疗代谢性疾病方面是有用的。
• Dneprovskii, A. S.; Mil'tsov, S. A., Journal of Organic Chemistry USSR (English Translation), 1986, vol. 22, p. 265 - 269
  作者：Dneprovskii, A. S.、Mil'tsov, S. A.

  DOI：——

  日期：——
• TREAD ENHANCEMENT ADDITIVES
  申请人：Kraton Chemical, LLC.

  公开号：EP3504266A2

  公开（公告）日：2019-07-03
• US9274419B2
  申请人：——

  公开号：US9274419B2

  公开（公告）日：2016-03-01
• [EN] TREAD ENHANCEMENT ADDITIVES<br/>[FR] ADDITIFS D'AMÉLIORATION DE BANDE DE ROULEMENT
  申请人：KRATON CHEMICAL LLC

  公开号：WO2018057726A2

  公开（公告）日：2018-03-29

  Provided herein are novel tire tread compositions. The tire tread compositions include a rubber, a terpene-based resin and at least one filler. The terpene-based resin comprises one terpene-based monomer such as α-pinene, referred to as a homopolymer, or combinations of several terpene-based monomers selected from α-pinene, β-pinene, δ-3 carene, β-phellandrene and pyrolysates of α-pinene, β-pinene, δ-3 carene, δ-2 carene, turpentine, and combinations thereof. The terpene-based resin is generally substantially free of limonene. The terpene-based resin has a softening point of about 80°C to about 130°C, a number average molecular weight (Mn) ranging from about 500 g/mol to about 775 g/mol and a glass transition temperature (Tg) of from about 38°C to about 81°C. The tire tread composition having the terpene-based resin shows improvements of tan δ at 0 °, wet grip and rolling resistance as compared with the compositions without the terpene-based resin or comprising alpha methyl styrene resin.