(1R,3R)-1-(2,4-dihydroxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 哈马拉生物碱
• 英文名称: (1R,3R)-1-(2,4-dihydroxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid
• 化学式: C₁₈H₁₆N₂O₄
• 分子量: 324.3
• InChiKey: ARALPLKQENYHNR-GDBMZVCRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  24
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  113
• 氢给体数：
  4
• 氢受体数：
  4

文献信息

• Use of indole compounds for fat reduction and skin and soft tissue tightening
  申请人：Alevere Medical Corporation

  公开号：US10258605B2

  公开（公告）日：2019-04-16

  The present invention relates to indole compounds and compositions and uses thereof, including uses of the indole compounds and compositions for the reduction or removal of localized fat deposits and/or tightening of skin and soft tissue laxity in subjects. The indole compounds can be employed, for example, in the cosmetic sector or for producing pharmaceutical products.

  本发明涉及吲哚化合物和组合物及其用途，包括吲哚化合物和组合物用于减少或去除局部脂肪沉积和/或收紧受试者的皮肤和软组织松弛。例如，吲哚化合物可用于化妆品行业或生产医药产品。
• USE OF INDOLE COMPOUNDS FOR FAT REDUCTION AND SKIN AND SOFT TISSUE TIGHTENING
  申请人：Alevere Medical Corporation

  公开号：EP2968272B1

  公开（公告）日：2021-06-16
• [EN] USE OF INDOLE COMPOUNDS FOR FAT REDUCTION AND SKIN AND SOFT TISSUE TIGHTENING<br/>[FR] UTILISATION DE COMPOSÉS D'INDOLE POUR LA RÉDUCTION DES GRAISSES ET LE RESSERREMENT DE LA PEAU ET DES TISSUS MOUS
  申请人：ALEVERE MEDICAL CORP

  公开号：WO2014143125A1

  公开（公告）日：2014-09-18

  The present invention relates to indole compounds and compositions and uses thereof, including uses of the indole compounds and compositions for the reduction or removal of localized fat deposits and/or tightening of skin and soft tissue laxity in subjects. The indole compounds can be employed, for example, in the cosmetic sector or for producing pharmaceutical products.