2,2'-[[3-(二甲基氨基)丙基]亚氨基]二乙醇 | 57567-83-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 2,2'-[[3-(二甲基氨基)丙基]亚氨基]二乙醇
• 英文名称: 2,2'-{[3-(dimethylamino)propyl]imino}bisethanol
• 英文别名: 2-[(3-dimethylamino-propyl)-(2-hydroxy-ethyl)-amino]-ethanol；N,N-Dimethyl-N',N'-bis-(2-hydroxy-aethyl)-1,3-diamino-propan；Ethanol, 2,2'-[[3-(dimethylamino)propyl]imino]bis-；2-[3-(dimethylamino)propyl-(2-hydroxyethyl)amino]ethanol
• CAS: 57567-83-6
• 化学式: C₉H₂₂N₂O₂
• 分子量: 190.286
• InChiKey: RDOJBMGPKKSKCQ-UHFFFAOYSA-N

物化性质

• 沸点：
  164-175 °C(Press: 7 Torr)
• 密度：
  1.019±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.7
• 重原子数：
  13
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,2'-[[3-(二甲基氨基)丙基]亚氨基]二乙醇 在 氯化亚砜 作用下， 以 氯仿 为溶剂， 生成 N,N-Dimethyl-N',N'-bis-(2-chlor-ethyl)-1,3-diamino-propan
  参考文献：
  名称：

  Aiko,I., Chemical and pharmaceutical bulletin, 1961, vol. 9, p. 343 - 351

  摘要：

  DOI：
• 作为产物：
  描述：

  N,N-二甲基-3-氯丙胺 、 二乙醇胺 在 potassium carbonate 作用下， 以 丙醇 为溶剂， 生成 2,2'-[[3-(二甲基氨基)丙基]亚氨基]二乙醇
  参考文献：
  名称：

  Aiko,I., Chemical and pharmaceutical bulletin, 1961, vol. 9, p. 343 - 351

  摘要：

  DOI：

文献信息

• Amino alcohol derivatives, process for their production and pharmaceutical preparations and reagents containing these compounds
  申请人：Roche Diagnostics GmbH

  公开号：US20030236266A1

  公开（公告）日：2003-12-25

  The present invention concerns new amino alcohol derivatives, a process for their production as well as pharmaceutical preparations and reagents which contain these substances. The invention concerns pharmaceutical agents of the general formula I 1 in which A denotes hydrogen, a group NR 1 R 2 , a group NR 1 (CH 2 ) p NR 3 R 4 , a group (C═NH)NH 2 or a pyridinyl residue, B and D are the same or different and each denotes a bond, a C 1 to C 6 alkylene residue or a group NR 5 —C 2 to C 6 -alkylene, C denotes piperidinediyl or piperazinediyl, W and X are the same or different and each denotes a bond or a carbonyl group, Y and Z are the same or different and each denotes a saturated or unsaturated hydrocarbon residue with 7 to 24 carbon atoms, R 1 to R 5 are the same or different and each represents hydrogen or a C 1 to C 6 alkyl residue, m is an integer 0, 1 or 2 and if m equals 2 C can also independently of one another be piperidinediyl or piperazinediyl, n and o are the same or different and each denotes the integers 2, 3 or 4 and p denotes an integer from 2 to 6 as well as physiologically tolerated salts thereof, provided that hydrazine derivatives are not included and that m cannot be 0 if A denotes hydrogen or a group (C═NH)NH 2 and B and D being the same or different represent a bond or an alkylene residue.

  本发明涉及新的氨基醇衍生物，其生产方法以及含有这些物质的制药制剂和试剂。该发明涉及通式I1的药用剂，其中A表示氢、基团NR1R2、基团NR1(CH2)pNR3R4、基团(C═NH)NH2或吡啶基,B和D相同或不同，每个表示键、C1到C6烷基残基或基团NR5—C2到C6-烷基,C表示哌啶二基或哌嗪二基,W和X相同或不同，每个表示键或羰基,Y和Z相同或不同，每个表示具有7到24个碳原子的饱和或不饱和碳氢残基，R1到R5相同或不同，每个代表氢或C1到C6烷基残基，m是整数0、1或2，如果m等于2，则C也可以独立地是哌啶二基或哌嗪二基，n和o相同或不同，每个表示整数2、3或4，p表示2到6之间的整数，以及其生理耐受的盐，前提是不包括肼衍生物，并且如果A表示氢或基团(C═NH)NH2，且B和D相同或不同表示键或烷基残基，则m不能为0。
• CATALYST COMPOSITION FOR PRODUCTION OF POLYURETHANE RESIN AND METHOD FOR PRODUCING POLYURETHANE RESIN (AS AMENDED)
  申请人：Kometani Hiroyuki

  公开号：US20100130629A1

  公开（公告）日：2010-05-27

  Disclosed is a catalyst composition for polyurethane resin production which contains (A) triethylenediamine, (B) a specific polyisocyanurating catalyst and/or (C) a specific highly temperature-sensitive catalyst. By using this catalyst composition, a polyurethane resin can be molded with good curability, while suppressing initial reactivity. Consequently, a polyurethane resin having excellent moldability and fluidity can be produced with high productivity by using the catalyst composition. The thus-obtained polyurethane resin is suitably applicable to shoe soles. The component (B) is selected from the group consisting of alkali metal salts of carboxylic acids, quaternary ammonium compounds expressed as R 1 R 2 R 3 R 4 N + ,X − , N,N,N′-trimethylaminoethylethanolamine, and 2,4,6-tris(dimethylaminomethyl)phenol, while the component (C) is selected from the group consisting of triazole salts and benzotriazole salts of 1,8-diazabicyclo[5.4.0]undecene-7 or 1,5-diazabicyclo[4.3.0]nonene-5. The mixing ratio of the component (B) and/or the component (C) to the component (A) is from 2% by weight to 60% by weight.

  本发明涉及一种用于聚氨酯树脂生产的催化剂组合物，其包含（A）三乙二胺，（B）特定的聚异氰酸酯催化剂和/或（C）特定的高温敏感催化剂。通过使用这种催化剂组合物，可以制造具有良好可固化性的聚氨酯树脂，同时抑制初始反应性。因此，使用催化剂组合物可以生产具有出色的可塑性和流动性的聚氨酯树脂，并具有高生产率。因此制造的聚氨酯树脂适用于鞋底。组分（B）选自羧酸的碱金属盐、表示为R1R2R3R4N+，X−的季铵化合物、N，N，N′-三甲基氨基乙基乙醇胺和2,4,6-三（二甲胺甲基）苯酚组成的群，而组分（C）选自1,8-二氮杂双环[5.4.0]十一烯-7或1,5-二氮杂双环[4.3.0]壬烯-5的三唑盐和苯并三唑盐组成的群。组分（B）和/或组分（C）与组分（A）的混合比重为2重量％至60重量％。
• Lubricating oil composition
  申请人：SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V.

  公开号：EP0311166A1

  公开（公告）日：1989-04-12

  Lubricating oil composition comprising a lubricating base oil, one or more overbased alkaline earth metal salts of an aromatic carboxylic acid, a succinimide derivative being the reaction product of a hydrocarbyl-substituted succinic anhydride an an amine, and an anti-gelling agent which has been selected from a polyalkoxylated alcohol and an alkanolamine derivative.

  润滑油组合物，包括润滑基础油、一种或多种芳香族羧酸的过基碱土金属盐、琥珀酰亚胺衍生物（烃基取代的琥珀酸酐与胺的反应产物），以及抗胶凝剂（选自聚烷氧基化醇和烷醇胺衍生物）。
• SHEET-FORM LAUNDERING ARTICLE
  申请人：Kao Corporation

  公开号：EP1048722A1

  公开（公告）日：2000-11-02

  An economical sheet-form laundering article which has excellent flexibility and employs water-soluble bases having a low basis weight and in which the contents are inhibited from flying off or being lost. The article comprises a layer comprising at least one composition selected among a detergent composition, a fiber softener composition, and a bleaching agent composition and water-soluble bases respectively bonded to both sides of the layer. It has a flexibility parameter as calculated by a specific method of 3 to 6.

  一种经济的片状洗涤用品，它具有极佳的柔韧性，并采用了基重较低的水溶性基料，可防止内容物飞散或流失。该产品由一层组成，该层包括至少一种从洗涤剂组合物、纤维柔软剂组合物和漂白剂组合物中选出的组合物，以及分别粘合在该层两侧的水溶性碱。根据特定方法计算，其柔韧性参数为 3 至 6。
• Catalyst composition for the production of a polyurethane resin, and method for producing a polyurethane resin
  申请人：Tosoh Corporation

  公开号：EP1092737A2

  公开（公告）日：2001-04-18

  A catalyst composition for the production of a polyurethane resin, which comprises an amine compound of the following formula (1): wherein each of R1 and R2 which are independent of each other, is a C1-4 alkyl group, such alkyl groups bonded to each other directly or via a nitrogen atom or an oxygen atom to form a ring structure, a dimethylaminopropyl group or a diethylaminopropyl group, and R3 is a C2-16 straight chain or branched chain alkylene group, and an amine compound of the following formula (2): wherein each of R4 and R5 which are independent of each other, is a C1-4 alkyl group, such alkyl groups bonded to each other directly or via a nitrogen atom or an oxygen atom to form a ring structure, a dimethylaminopropyl group or a diethylaminopropyl group, R6 is a C2-16 straight chain or branched chain alkylene group, R7 is a C2-3 straight chain or branched chain alkylene group, and n is an integer of from 0 to 2.

  一种用于生产聚氨酯树脂的催化剂组合物，它包括下式(1)的胺化合物： 其中相互独立的 R1 和 R2 均为 C1-4 烷基，此类烷基直接或通过氮原子或氧原子相互键合以形成环状结构、二甲基氨基丙基或二乙基氨基丙基，R3 为 C2-16 直链或支链亚烷基，以及下式（2）的胺化合物： R4 和 R5 均为 C1-4 烷基，此类烷基直接或通过氮原子或氧原子相互键合以形成环状结构、二甲基氨基丙基或二乙基氨基丙基，R3 为 C2-16 直链或支链亚烷基： 其中相互独立的 R4 和 R5 各为 C1-4 烷基，此类烷基直接或通过氮原子或氧原子相互键合以形成环状结构、二甲基氨基丙基或二乙基氨基丙基，R6 为 C2-16 直链或支链亚烷基，R7 为 C2-3 直链或支链亚烷基，n 为 0 至 2 的整数。