2,2'-二萘基砜 | 26189-33-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 中文名称: 2,2'-二萘基砜
• 英文名称: 2,2-dinaphthylsulfone
• 英文别名: Dinaphthyl-(2)-sulfon；Binaphthyl sulfone；2-naphthalen-2-ylsulfonylnaphthalene
• CAS: 26189-33-3
• 化学式: C₂₀H₁₄O₂S
• 分子量: 318.396
• InChiKey: RIUSNQJIDQVTEH-UHFFFAOYSA-N

物化性质

• 熔点：
  143-144 °C
• 沸点：
  557.6±19.0 °C(Predicted)
• 密度：
  1.294±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  23
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  42.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,2'-二萘基砜 在 sulfur 作用下， 生成 bis(2-naphthyl)sulfide
  参考文献：
  名称：

  Krafft; Vorster, Chemische Berichte, 1893, vol. 26, p. 2821

  摘要：

  DOI：
• 作为产物：
  描述：

  bis(2-naphthyl)sulfide 在 铬酸 、 溶剂黄146 作用下， 生成 2,2'-二萘基砜
  参考文献：
  名称：

  Krafft, Chemische Berichte, 1890, vol. 23, p. 2363

  摘要：

  DOI：

文献信息

• Synthesis of Symmetrical Diaryl Sulfone by Homocoupling of Sodium Arylsulfinate
  作者：Yao Peng

  DOI：10.3184/174751914x13946336636551

  日期：2014.5

  An efficient practical homocoupling reaction of sodium arylsulfinate promoted by Cu(II) is reported whereby symmetrical diaryl sulfone derivatives are obtained with high selectivity and reactivity by intermolecular cross-coupling. This homocoupling reaction is tolerant to many functional groups and proceeds under mild conditions.

  报道了一种由 Cu(II) 促进的芳基亚磺酸钠的有效实际均偶联反应，通过分子间交叉偶联以高选择性和反应性获得对称的二芳基砜衍生物。这种同偶联反应对许多官能团具有耐受性，并且在温和的条件下进行。
• Intramolecular Desulfitative Coupling: Nickel-Catalyzed Transformation of Diaryl Sulfones into Biaryls via Extrusion of SO₂
  作者：Fumiya Takahashi、Keisuke Nogi、Hideki Yorimitsu

  DOI：10.1021/acs.orglett.8b02972

  日期：2018.10.19

  As a new transformation of organosulfur compounds, intramolecular desulfitative coupling of diaryl sulfones to the corresponding biaryls has been developed with the aid of nickel–NHC catalysts. This catalytic elimination of SO2 was also applicable to alkenyl aryl sulfone to furnish the corresponding alkenyl arene.

  作为有机硫化合物的新转变，借助于镍-NHC催化剂，已开发出二芳基砜与相应的联芳基的分子内脱硫偶联。SO 2的这种催化消除也适用于烯基芳基砜以提供相应的烯基芳烃。
• Identification of the Temporal Components of Seizure Onset in the Scalp EEG
  作者：Nora S. O'Neill、Zoltan J. Koles、Manouchehr Javidan

  DOI：10.1017/s0317167100001402

  日期：2001.8

  The identification of the earliest indication of rhythmical oscillations and paroxysmal events associated with an epileptic seizure is paramount in identifying the location of the seizure onset in the scalp EEG. In this work, data-dependent filters are designed that can help reveal obscure activity at the onset of seizures in problematic EEGs.

  Data-dependent filters were designed using temporal patterns common to selected segments from pre-ictal and ictal portions of the scalp EEG. Temporal patterns that accounted for more variance in the ictal segment than in the pre-ictal segment of the scalp EEG were used to form the filters.

  Application of the filters to the scalp EEG revealed temporal components in the seizure onset in the scalp recording that were not obvious in the unfiltered EEG. Examination of the filtered EEG enabled the onset of the seizure to be recognized earlier in the recording. The utility of the filters was confirmed qualitatively by comparing the scalp recording to the intracranial recording and quantitatively by calculating correlation coefficients between the scalp and intracranial recordings before and after filtering.

  The data-dependent approach to EEG filter design allows automatic detection of the basic frequencies present in the seizure onset. This approach is more effective than narrow band-pass filtering for eliminating artifactual and other interference that can obscure the onset of a seizure. Therefore, temporal-pattern filtering facilitates the identification of seizure onsets in challenging scalp EEGs.

  背景：识别与癫痫发作相关的节律性振荡和阵发性事件的最早迹象，对于确定头皮脑电图中癫痫发作的起始位置至关重要。方法：利用头皮脑电图发作前和发作期部分所选片段的共同时间模式设计了数据依赖性滤波器。结果：将滤波器应用于头皮脑电图，发现了头皮记录中癫痫发作开始的时间成分，而这些成分在未经滤波的脑电图中并不明显。对过滤后的脑电图进行检查，可以在记录中更早地识别出癫痫发作的起始时间。通过比较头皮记录和颅内记录，对滤波器的效用进行了定性确认；通过计算头皮记录和颅内记录在滤波前后的相关系数，对滤波器的效用进行了定量确认。与窄带通滤波器相比，这种方法能更有效地消除可能掩盖癫痫发作起始点的假性干扰和其他干扰。因此，时间模式滤波有助于在具有挑战性的头皮脑电图中识别癫痫发作的起始点。
• Palladium-catalyzed One-step Synthesis of Symmetrical Diaryl Sulfones from Aryl Halides and a Sulfur Dioxide Surrogate
  作者：Hiromichi Tanaka、Hideyuki Konishi、Kei Manabe

  DOI：10.1246/cl.190300

  日期：2019.8.5

  A convenient method for the one-step synthesis of symmetrical diaryl sulfones from aryl halides has been developed. A keystone of the method is the use of K2S2O5, which can be easily and safely han...

  已经开发了一种从芳基卤化物一步合成对称二芳基砜的简便方法。该方法的一个关键是使用 K2S2O5，它可以轻松安全地处理...
• OPTICAL FILTER
  申请人：Mae Yukiko

  公开号：US20110152538A1

  公开（公告）日：2011-06-23

  An optical filter containing at least one naphtholactam derivative represented by general formula (I), wherein X is oxygen or sulfur; R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , and Y are each hydrogen, halogen, nitro, cyano, aldehyde, carboxyl, hydroxyl, —NRR′, organosilyl, optionally substituted C1-C30 alkyl, optionally substituted C6-C30 aryl, or optionally substituted C7-C30 arylalkyl; and R and R′ are each hydrogen, optionally substituted C1-C30 alkyl, or optionally substituted C6-C30 aryl.

  一个包含至少一种由通式（I）表示的萘内酰胺衍生物的光学滤光片，其中X是氧或硫；R1、R2、R3、R4、R5、R6和Y分别是氢、卤素、硝基、氰基、醛基、羧基、羟基、—NRR′、有机硅基、可选地取代的C1-C30烷基、可选地取代的C6-C30芳基或可选地取代的C7-C30芳基烷基；R和R′分别是氢、可选地取代的C1-C30烷基或可选地取代的C6-C30芳基。