2,3-二甲氧基-6,7-二甲基萘 | 4676-58-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 中文名称: 2,3-二甲氧基-6,7-二甲基萘
• 英文名称: 2,3-Dimethoxy-6,7-dimethyl-naphthalin
• 英文别名: Pyroguajacinmethylaether；Methylpyroguaiacin；2,3-dimethoxy-6,7-dimethyl-naphthalene；2,3-Dimethoxy-6,7-dimethylnaphthalene
• CAS: 4676-58-8
• 化学式: C₁₄H₁₆O₂
• 分子量: 216.28
• InChiKey: DVLHJCSVJIHUCL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,3-二甲氧基-6,7-二甲基萘 在 sodium dichromate 、 溶剂黄146 作用下， 生成 6,7-dimethoxy-2,3-dimethyl-1,4-naphtoquinone
  参考文献：
  名称：

  Schroeter; Lichtenstadt; Irineu, Chemische Berichte, 1918, vol. 51, p. 1600

  摘要：

  DOI：
• 作为产物：
  描述：

  6,7-bis-chloromethyl-naphtho[2,3-d][1,3]dioxole 在 palladium on activated charcoal 、 五氯化磷 、 溶剂黄146 、 苯 作用下， 生成 2,3-二甲氧基-6,7-二甲基萘
  参考文献：
  名称：

  天然酚醛树脂的成分。第二十三部分。芝麻素的组成

  摘要：

  DOI：

  10.1039/jr9550000827

文献信息

• On the Biosynthesis of the Benzimidazole Bases Occurring in Corrinoids
  作者：Paul Renz、Andrée J. Bauer-David

  DOI：10.1515/znb-1972-0513

  日期：1972.5.1

  implicates the possible existence of a corrinoid containing 6′,7′-dimethylnaphtho- (2′,3′) -imidazole-4,5 (DMNIA). In order to facilitate the detection of this corrinoid in natural sources by means of a reference compound, DMNIA was synthesized and added to cultures of Propionibacterium shermanii. Thus the new vitamin B12-analog DMNIA-cobamide was formed. The DMNIA-cobamide was degraded and its base isolated

  Bernhauer 关于类可啉的苯并咪唑碱基的生物合成的假设暗示可能存在含有 6',7'-二甲基萘-(2',3')-咪唑-4,5 (DMNIA) 的类可啉。为了便于通过参考化合物检测天然来源中的这种类可啉，合成了 DMNIA 并将其添加到谢尔曼丙酸杆菌的培养物中。因此形成了新的维生素 B12 类似物 DMNIA-cobamide。DMNIA-cobamide 被降解并分离其碱。该碱与通过化学合成制备的产物具有相同的紫外光谱和电泳行为。DMNIA-cobamide 与氢氧化铈降解形成 DMNIA-α-D-呋喃核糖苷。DMNIA-cobamide 的高氯酸处理产生 DMNIA-α-D-呋喃核糖苷 3'-磷酸。用需要维生素 B,12 的莱氏乳杆菌 ATCC 7830 测试的 DMNIA-氰化钴的微生物活性与维生素 B12 的活性相同，大肠杆菌突变体 113-3 表现出约 50% 的生长活性维生素
• The role of human and mouse Y chromosome genes in male infertility
  作者：Nabeel A. Affara、M. J. Mitchell

  DOI：10.1007/bf03343787

  日期：2000.11

  It was suggested by Ronald Fisher in 1931 that genes involved in benefit to the male (including spermatogenesis genes) would accumulate on the Y chromosome. The analysis of mouse Y chromosome deletions and the discovery of microdeletions of the human Y chromosome associated with diverse defective spermatogenic phenotypes has revealed the presence of intervals containing one or more genes controlling male germ cell differentiation. These intervals have been mapped, cloned and examined in detail for functional genes. This review discusses the genes mapping to critical spermatogenesis intervals and the evidence indicating which are the most likely candidates underlying Y-linked male infertility. (C) 2000, Editrice Kurtis.
• BICYCLO COMPOUND, METHOD FOR PRODUCING PENTACENE AND A FILM THEREOF USING THE SAME, AND METHOD FOR PRODUCING BICYCLO COMPOUND
  申请人：Uno Hidemitsu

  公开号：US20090317753A1

  公开（公告）日：2009-12-24

  A method for producing highly purified fused aromatic ring compounds with high yield by a simpler method. A method for producing a fused aromatic ring compound comprising irradiating the bicyclo compound containing at least one bicyclo ring represented by formula (1) in a molecule with light to detach a leaving group X from a residual part to form an aromatic ring: wherein R 1 and R 3 each denotes a group to form an aromatic ring or a heteroaromatic ring which may be substituted, together with a group to which each thereof is bonded; R 2 and R 4 each denotes a hydrogen atom, an alkyl group, an alkoxy group, an ester group or a phenyl group; and X is a leaving group, which denotes a carbonyl group or —N═.
• US7601478B2
  申请人：——

  公开号：US7601478B2

  公开（公告）日：2009-10-13
• US7884249B2
  申请人：——

  公开号：US7884249B2

  公开（公告）日：2011-02-08