2-(2-氯-1-二乙氧基磷酰硫基-乙基)异吲哚-1,3-二酮 | 18776-60-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异吲哚及其衍生物
• 中文名称: 2-(2-氯-1-二乙氧基磷酰硫基-乙基)异吲哚-1,3-二酮
• 英文名称: dialifos
• 英文别名: Phosphorothioic acid, S-(2-chloro-1-(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)ethyl) O,O-diethyl ester；2-(2-chloro-1-diethoxyphosphorylsulfanylethyl)isoindole-1,3-dione
• CAS: 18776-60-8
• 化学式: C₁₄H₁₇ClNO₅PS
• 分子量: 377.785
• InChiKey: DGFSZLIRMFVRBS-UHFFFAOYSA-N

物化性质

• 沸点：
  458.7±55.0 °C(Predicted)
• 密度：
  1.417±0.06 g/cm3(Predicted)
• 保留指数：
  2482

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  23
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  98.2
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Outdoor films stabilized against chemical attack
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0214507B1

  公开（公告）日：1992-01-15
• NOVEL PHOSPHOTRIESTERASE ENZYMES, METHODS AND COMPOSITIONS RELATED THERETO
  申请人：Polytechnic Institute of New York University

  公开号：US20160083702A1

  公开（公告）日：2016-03-24

  The instant invention provides methods and related compositions for identifying polypeptides with improved stability and/or enzymatic activity in comparison to native forms, wherein the identified polypeptides comprise one or more non-natural amino acids. In certain embodiments, the present invention relates to novel phosphotriesterase enzymes comprising one or more non-natural amino acids. In a particular embodiment, the instant invention provides novel phosphotriesterase enzymes with greater stability and/or enhanced activity in comparison to native forms of the enzyme. The present invention also relates to compositions comprising novel phophotriesterase enzymes, such as prophylactics, decontaminants, animal feedstocks, and assay kits.
• US9617525B2
  申请人：——

  公开号：US9617525B2

  公开（公告）日：2017-04-11