sec-butyl-(9H-fluoren-2-yl)-amine | 350016-06-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 芴
• 英文名称: sec-butyl-(9H-fluoren-2-yl)-amine
• 英文别名: N-butan-2-yl-9H-fluoren-2-amine
• CAS: 350016-06-7
• 化学式: C₁₇H₁₉N
• mdl: MFCD11125181
• 分子量: 237.345
• InChiKey: OKPHNSXHHUBWGN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.1
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.294
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Tricyclic compounds and method of treating herpes virus
  申请人：——

  公开号：US20030229073A1

  公开（公告）日：2003-12-11

  The present invention provides a compound of the formula (I) and pharmaceutically acceptable salts having useful antiviral activity against viruses of the herpes family. In said formula, X=O, (CH 2 ) m , S, SO, SO 2 , NH, NR 8 or a chemical bond; Y=O, (CH 2 ) m , S, SO, SO 2 , NH, NR 8 ; Z=NH, O, NR 8 , S, SO, SO 2 . The remaining substituents are described in the specification.

  本发明提供了一种公式(I)的化合物及其药学上可接受的盐，对于单纯疱疹病毒家族的病毒具有有用的抗病毒活性。在该式中，X=O、(CH2)m、S、SO、SO2、NH、NR8或化学键；Y=O、(CH2)m、S、SO、SO2、NH、NR8；Z=NH、O、NR8、S、SO、SO2。其余的取代基在说明书中描述。
• TRICYCLIC COMPOUNDS WITH ANTIVIRAL ACTIVITY
  申请人：WARNER-LAMBERT COMPANY

  公开号：EP1248777A2

  公开（公告）日：2002-10-16
• Tricyclic compounds with antiviral activity
  申请人：Booth John Richard

  公开号：US20050075332A1

  公开（公告）日：2005-04-07

  The present invention provides a compound of the formula (I) and pharmaceutically acceptable salts having useful antiviral activity against viruses of the herpes family. In said formula, X═O, (CH 2 ) m , S, SO, SO 2 , NH, NR 8 , or a chemical bond; Y═O, (CH 2 ) m , S, SO, SO 2 , NH, NR 8 ; Z=NH, O, NR 8 , S, SO, SO 2 . The remaining substituents are described in the specification.
• US6800656B2
  申请人：——

  公开号：US6800656B2

  公开（公告）日：2004-10-05
• [EN] TRICYCLIC COMPOUNDS AND METHOD OF TREATING HERPES VIRUS<br/>[FR] COMPOSES TRICYCLIQUES ET PROCEDES DE TRAITEMENT DES HERPESVIRUS
  申请人：WARNER LAMBERT CO

  公开号：WO2001051479A2

  公开（公告）日：2001-07-19

  The present invention provides a compound of the formula (I) and pharmaceutically acceptable salts having useful antiviral activity against viruses of the herpes family. In said formula, X = O, (CH2)m, S, SO, SO2, NH, NR8 or a chemical bond; Y = O, (CH2)m, S, SO, SO2, NH, NR8; Z = NH, O, NR8, S, SO, SO2. The remaining substituents are described in the specification.