8-[(2,4-Dimethylthiophen-3-yl)methylamino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并吡啶类
• 英文名称: 8-[(2,4-Dimethylthiophen-3-yl)methylamino]-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxamide
• 化学式: C₁₇H₂₀N₄OS
• 分子量: 328.4
• InChiKey: JXDIFRRRYRQRPX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  101
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Pyrrolo [2,3-C] Pyridine Compound, Process for Producing the Same, and Use
  申请人：Hasuoka Atsushi

  公开号：US20070293532A1

  公开（公告）日：2007-12-20

  Provision of a compound having a superior proton pump action, which shows an antiulcer activity and the like after conversion to an in vivo proton pump inhibitor, a production method thereof and use thereof. A pyrrolo[2,3-c]pyridine compound represented by the formula: wherein each symbol is as defined in the specification.

  提供一种具有卓越质子泵作用的化合物，经转化为体内质子泵抑制剂后，表现出抗溃疡活性等，其生产方法和用途。一种由以下式表示的吡咯并[2,3-c]吡啶化合物：其中每个符号如规范中所定义。
• PYRROLOÝ2,3-c¨PYRIDINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE
  申请人：Takeda Pharmaceutical Company Limited

  公开号：EP1787991A1

  公开（公告）日：2007-05-23

  Provision of a compound having a superior proton pump action, which shows an antiulcer activity and the like after conversion to an in vivo proton pump inhibitor, a production method thereof and use thereof. A pyrrolo[2,3-c]pyridine compound represented by the formula: wherein each symbol is as defined in the specification.

  提供一种具有优异质子泵作用的化合物，该化合物在转化为体内质子泵抑制剂后显示出抗溃疡活性等作用，及其生产方法和用途。 一种由式表示的吡咯并[2,3-c]吡啶化合物： 其中各符号如说明书中所定义。
• PYRROLO[2,3-c]PYRIDINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE
  申请人：Takeda Pharmaceutical Company Limited

  公开号：EP1787991B2

  公开（公告）日：2020-06-24
• NOVEL IMIDAZOPYRIDINE COMPOUNDS WITH THERAPEUTIC EFFECT
  申请人：AstraZeneca AB

  公开号：EP1421083A1

  公开（公告）日：2004-05-26
• Novel imidazopyridine compounds with therapeutic effect
  申请人：——

  公开号：US20040220209A1

  公开（公告）日：2004-11-04

  The present invention relates to imidazo pyridine derivatives of the formula (I) whichinhibit exogenously or endogenously stimulated gastric acid secretion and thus can be usedin the prevention and treatment of gastrointestinal inflammatory diseases. (I)