溴-氯-碘甲烷 | 34970-00-8

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 卤代烷
• 中文名称: 溴-氯-碘甲烷
• 中文别名: 溴氯碘甲烷
• 英文名称: bromochloroiodomethane
• 英文别名: BCIM；bromo-chloro-iodo-methane；Brom-chlor-jod-methan；Brom-chlor-iodmethan；Bromchloriodmethan；Chlorbromiodmethan；bromo-chloro-iodomethane
• CAS: 34970-00-8
• 化学式: CHBrClI
• 分子量: 255.28
• InChiKey: WUHPSARYLVYQOT-UHFFFAOYSA-N

物化性质

• 熔点：
  5 °C
• 沸点：
  180-190 °C
• 密度：
  2.932-3.120 g/cm3
• 溶解度：
  溶于丙酮
• 保留指数：
  883

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  4
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

安全信息

• 海关编码：
  2903799090

反应信息

• 作为反应物：
  描述：

  溴-氯-碘甲烷 在 air 作用下， 生成 carbonyl bromide chloride
  参考文献：
  名称：

  Garino; Teofili, Gazzetta Chimica Italiana, 1926, vol. 56, p. 849

  摘要：

  DOI：
• 作为产物：
  描述：

  氯二溴甲烷 在 甲醇 、 sodium methylate 、 sodium iodide 作用下， 生成 溴-氯-碘甲烷
  参考文献：
  名称：

  Methylene Derivatives as Intermediates in Polar Reactions. XIII. The Basic Hydrolysis of Bromochloroiodomethane¹

  摘要：

  DOI：

  10.1021/ja01549a040

文献信息

• Novel synthetic approaches to CHBrFI, CHClFI and CHBrClI
  作者：Dong Bo Li、Siu-Choon Ng、Igor Novak

  DOI：10.1016/s0040-4020(02)00532-x

  日期：2002.7

  described. Mercuric fluoride was found to be an effective fluorinating agent in fluorinations of CHI2Br (6) and CHI2Cl (8) to yield CHBrFI, CHClFI, respectively. Chlorination of CHI2Br (6) by using antimony pentachloride as a chlorinating agent, afforded CHBrClI in convenient and mild condition.

  描述了三种制备CHBrFI，CHClFI和CHBrClI外消旋混合物的简便方法。发现氟化汞是在CHI 2 Br（6）和CHI 2 Cl（8）氟化反应中分别生成CHBrFI，CHClFI的有效氟化剂。通过使用五氯化锑作为氯化剂对CHI 2 Br（6）进行氯化，可在方便温和的条件下提供CHBrClI。
• Determination, synthesis and survey of iodinated trihalomethanes in water treatment processes
  作者：B Cancho

  DOI：10.1016/s0043-1354(00)00079-8

  日期：2000.9.1

  Trihalomethanes (THMs) are formed as a result of the interaction of free aqueous chlorine, used as a disinfectant in drinking water, with the organic matter in raw water. Although chlorinated, brominated and chlorobromotrihalomethanes are the most common disinfection by-products reported, iodinated trihalomethanes (ITHMs) can be formed when iodide is present in raw water, ITHMs have been usually associated with several medicinal or pharmaceutical taste and odor events in drinking water. For instance, the odor and taste threshold concentrations of iodoform are 0.02 and 5 mu g/l, respectively. Different analytical techniques have been studied to identify these compounds but their quantitative determination has not been performed due to the lack of commercial standards. In this study ITHMs (CHCl2I, CHClI2, CHBr2I, CHBrI2 and CHBrClI) have been synthesized in order to evaluate headspace (HS), purge and trap (P&T), closed loop stripping analysis (CLSA) and liquid-liquid extraction (LLE) as analytical methods for determination. HS and LLE were followed by gas chromatography and electron capture detector (GC/ECD); whereas P&T and CLSA with gas chromatography and mass spectrometry (GC/MS). The most appropriate method, LLE/GC/ECD, was applied to evaluate the stability of ITHMs in water (ultrapure, raw and treated water) in order to confirm their presence in tap water. Ascorbic acid was the quenching reagent chosen to avoid free chlorine at the time of sample collection. Finally, samples from the different stages of the treatment plant in Barcelona (NE Spain) were analyzed. Only three (CHCl2I, CHBrClI and CHBr2I) of the six ITHMs were identified and determined, at average levels lower than 1 mu g/l, in sand filtered and ozonated waters. No ITHMs were identified in distribution system water. (C) 2000 Elsevier Science Ltd. All rights reserved.
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: C: MVol.D3, 2.6.1, page 120 - 120
  作者：

  DOI：——

  日期：——
• Garino, M.; Teofili, E., Gazzetta Chimica Italiana, 1926, vol. 56, p. 847 - 852
  作者：Garino, M.、Teofili, E.

  DOI：——

  日期：——
• Garino; Muzio, Gazzetta Chimica Italiana, 1922, vol. 52 II, p. 229
  作者：Garino、Muzio

  DOI：——

  日期：——