4-(1-methoxymethyl)-2-(3'-methoxy-4'-hydroxyphenyl)-1,3-dioxolane | 918789-80-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-(1-methoxymethyl)-2-(3'-methoxy-4'-hydroxyphenyl)-1,3-dioxolane
• 英文别名: 4-(1-methoxymethyl)-2-(3'-methoxy-4'-hydroxyphenyl)-1,3-dioxolan；4-(methoxymethyl)-2-(3'-methoxy-4'-hydroxyphenyl)-1,3-dioxolane；2-Methoxy-4-[4-(methoxymethyl)-1,3-dioxolan-2-yl]phenol
• CAS: 918789-80-7
• 化学式: C₁₂H₁₆O₅
• 分子量: 240.256
• InChiKey: JTCGDUNRKVXIKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  57.2
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• (3R)-L-MENTHYL 3-HYDROXYBUTYRATE, PROCESS FOR PRODUCING THE SAME, AND SENSATE COMPOSITION COMPRISING THE SAME
  申请人：HOJO Kazuma

  公开号：US20100280110A1

  公开（公告）日：2010-11-04

  The present invention provides a cooling component or sensate component which has further strong cooling intensity and is excellent in the persistency or refresh-feeling and cool-feeling, a sensate composition comprising the same, and various products comprising the sensate composition. The present invention relates to, as a cooling component or sensate component, (3R)-1-menthyl 3-hydroxybutyrate represented by the following formula (I):

  本发明提供了一种具有更强的冷却强度，且在持久性或清爽感和凉爽感方面表现出色的冷却成分或感知成分，以及包含该成分的感知组合物和包含感知组合物的各种产品。本发明涉及一种冷却成分或感知成分，即由以下式（I）表示的（3R）-1-薄荷基3-羟基丁酸丁酯。
• PROCESS FOR PRODUCING (3S)-I-MENTHYL 3-HYDROXYBUTYRATE AND SENSATE COMPOSITION
  申请人：HOJO Kazuma

  公开号：US20100303740A1

  公开（公告）日：2010-12-02

  The present invention provides a cooling component or sensate component which does not have undesirable stimulus feeling, bitterness and the like and is excellent in the persistence of refresh-feeling and cool-feeling, a sensate composition which comprises the same, and various products that comprise said sensate composition. The present invention relates to a cooling agent comprising (3S)-1-menthyl 3-hydroxybutyrate represented by the following formula (I)

  本发明提供了一种不具有不良刺激感、苦味等特性且在保持清爽感和凉爽感方面表现出色的冷却成分或感知成分，以及包含相同成分的感知组合物，以及包含所述感知组合物的各种产品。本发明涉及一种包含以下化学式（I）所代表的（3S）-1-薄荷基-3-羟基丁酸酯的冷却剂。
• P-MENTHANE-3,8-DIOL ISOMER MIXTURE, COOLING SENSATION COMPOSITION COMPRISING THE SAME, AND PRODUCT COMPRISING THE COOLING SENSATION COMPOSITION
  申请人：Komatsuki Yasuhiro

  公开号：US20140219931A1

  公开（公告）日：2014-08-07

  The present invention relates to a p-menthane-3,8-diol isomer mixture 50% by mass or more of which is constituted of (1S)-isomers and a cooling sensation composition containing this mixture. The present invention also relates to a flavor and/or fragrance composition, food, beverage, cosmetic, daily use product, oral cavity composition, or pharmaceutical containing the p-menthane-3,8-diol isomer mixture in an amount of 0.0001 to 90% by mass.

  本发明涉及一种p-薄荷烷-3,8-二醇异构体混合物，其中50%或更多的质量由(1S)-异构体构成，以及含有该混合物的冷感组合物。本发明还涉及一种口味和/或香料组合物、食品、饮料、化妆品、日常用品、口腔组合物或药物，其中p-薄荷烷-3,8-二醇异构体混合物的质量占0.0001至90%。
• Flavor and fragrance composition
  申请人：Aida Takashi

  公开号：US20090275669A1

  公开（公告）日：2009-11-05

  A flavor and fragrance composition with a cooling sensation effect comprising 1-(2-hydroxy-4-methylcyclohexyl)ethanone represented by the formula (1). The flavor and fragrance composition is added to a beverage or food product, a fragrance or cosmetic product, a daily utensil product, an oral composition, or a pharmaceutical product in the range of 0.0001 to 20% by weight to the total weight of the flavor and fragrance composition added.

  一种具有冰凉感效果的香味和香料组合物，包括由式（1）表示的1-(2-羟基-4-甲基环己基)乙酮。该香味和香料组合物被添加到饮料或食品产品、香水或化妆品产品、日用品产品、口腔组合物或制药产品中，添加量为香味和香料组合物总重量的0.0001至20%。
• Menthol Dearivative and Cooling Agent Composition Comprising the Same
  申请人：Ishida Kenya

  公开号：US20070225378A1

  公开（公告）日：2007-09-27

  The invention relates to innovative menthol derivatives which are represented by the general formula (I) below and are excellent in a cooling effect and cool retaining effect, cooling agent compositions comprising the menthol derivatives, and sensory stimulation agent compositions containing the cooling agent compositions, as well as fragrance compositions, beverage or food products, cosmetic products, toiletry products, bathing agents, and pharmaceutical products containing the cooling agent compositions or sensory stimulation agent compositions. (general formula (I)) wherein R<1> represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, or an acyl group having 1 to 5 carbon atoms; R<2> and R<3> independently represent an alkylene group having 2 to 5 carbon atoms and optionally having a substituent; double dotted line represents a single bond or a double bond; and n is an integer of 1 to 3.

  本发明涉及一种创新的薄荷醇衍生物，其由下述通式（I）表示，并且在冷却效果和保持冷却效果方面表现出色，包括该薄荷醇衍生物的冷却剂组合物、含有该冷却剂组合物的感官刺激剂组合物、以及包含该冷却剂组合物或感官刺激剂组合物的香料组合物、饮料或食品产品、化妆品、卫生用品、沐浴剂和药品。 其中，R1代表氢原子、具有1到4个碳原子的烷基或具有1到5个碳原子的酰基；R2和R3独立地代表具有2到5个碳原子的烷基，并且可以具有取代基；双点线表示单键或双键；n为1到3的整数。