[4-[5-(4-dihexylamino)phenyl]thiophene-2-yl]-1-methyl pyridinium methane sulfonate | 1236567-77-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: [4-[5-(4-dihexylamino)phenyl]thiophene-2-yl]-1-methyl pyridinium methane sulfonate
• 英文别名: N,N-dihexyl-4-[5-(1-methylpyridin-1-ium-4-yl)thiophen-2-yl]aniline;methanesulfonate
• CAS: 1236567-77-3
• 化学式: CH₃O₃S*C₂₈H₃₉N₂S
• 分子量: 530.796
• InChiKey: FCRFPHCDPDYTGM-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  7.04
• 重原子数：
  36
• 可旋转键数：
  13
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  101
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  N,N-dihexyl-4-iodoaniline 在 四(三苯基膦)钯 sodium carbonate 作用下， 以 甲醇 、 二氯甲烷 、 甲苯 为溶剂， 反应 39.5h， 生成 [4-[5-(4-dihexylamino)phenyl]thiophene-2-yl]-1-methyl pyridinium methane sulfonate
  参考文献：
  名称：

  EP2395055

  摘要：

  公开号：

文献信息

• FLUORESCENT SOLVATOCHROMIC PIGMENT
  申请人：Yamada Koji

  公开号：US20120015399A1

  公开（公告）日：2012-01-19

  The present invention presents a novel fluorescent solvatochromic dye that (1) has an ionic terminal that makes it easier to use in a hydrophilic surface or in polar solvents, (2) can be efficiently excited by commonly used Argon lasers (488 nm), (3) shifts the wavelength of emitted light according to the change of polarity, and (4) can effectively stain living tissues such as cells and the like. A pyridinium group was introduced to the electron attracting group of the neutral fluorescent solvatochromic dye (Japanese Patent Application Public Disclosure No. 20008-291210 A) displaying an excellent emission wavelength response and synthesized a fluorescent solvatochromic dye. Then it was found that the fluorescence wavelength of the fluorescent solvatochromic dye changed extensively when the polarity changed on a hydrophilic surface and that the fluorescent solvatochromic dye, when altered to a cationic form, stained cell membranes and could be used to observe the behavior thereof.
• EP2395055
  申请人：——

  公开号：——

  公开（公告）日：——