申请人:Toray Industries, Inc.
公开号:EP3438243A1
公开(公告)日:2019-02-06
The present invention relates to a method for filtering a microbial culture solution using a membrane module, said method comprising four stages including (a) cross-flow filtration of the microbial culture solution, (b) rinsing with water, (c) washing with a chemical solution and (d) rinsing with water, wherein: the filtrate passing through the membrane module in the cross-flow filtration has a total sugar concentration of 1,000-100,000 mg/l inclusive and a protein concentration of 50-1,000 mg/l inclusive; the aforesaid stage (c) comprises step (c-1) for washing with a chemical solution containing a hypochlorite and a nonionic surfactant; and the aforesaid stages (a) to (d) are repeated in this order.
本发明涉及一种使用膜组件过滤微生物培养液的方法,所述方法包括四个阶段,包括(a)微生物培养液的错流过滤,(b)用水冲洗,(c)用化学溶液洗涤,以及(d)用水冲洗,其中:在横流过滤中通过膜组件的滤液的总糖浓度为 1,000-100,000 毫克/升(含),蛋白质浓度为 50-1,000 毫克/升(含);上述阶段(c)包括用含有次氯酸盐和非离子表面活性剂的化学溶液进行洗涤的步骤(c-1);按此顺序重复上述阶段(a)至(d)。