1,2,3,4-tetrahydronaphthacene-6,11-quinone | 5349-90-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 并四苯
• 英文名称: 1,2,3,4-tetrahydronaphthacene-6,11-quinone
• 英文别名: 1,2,3,4-Tetrahydro-6,11-tetracenequinone；7,8,9,10-tetrahydro-naphthacenee-5,12-dione；1,2,3,4-Tetrahydro-6,11-naphthacenequinone；7,8,9,10-Tetrahydro-naphthacen-5,12-dion；1,2,3,4-Tetrahydro-6,11-dioxonaphthacen；1.2.3.4-Tetrahydro-naphthacenchinon-(9.10)；7,8,9,10-tetrahydro-naphthacene-5,12-dione；2.3-Tetramethylen-anthrachinon；7,8,9,10-Tetrahydrotetracene-5,12-dione
• CAS: 5349-90-6
• 化学式: C₁₈H₁₄O₂
• 分子量: 262.308
• InChiKey: XFOHBSLKSOSFBE-UHFFFAOYSA-N

物化性质

• 熔点：
  211 °C
• 沸点：
  480.6±45.0 °C(Predicted)
• 密度：
  1.273±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  20
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2914690090

反应信息

• 作为反应物：
  描述：

  1,2,3,4-tetrahydronaphthacene-6,11-quinone 生成 并四苯
  参考文献：
  名称：

  Dufraisse; Horclois, Bulletin de la Societe Chimique de France, 1936, vol. <5> 3, p. 1880,1891

  摘要：

  DOI：
• 作为产物：
  描述：

  2,3-二溴-1,4-萘醌 在 copper(l) iodide 、 四(三苯基膦)钯 哌啶 、 potassium fluoride 、 正丁基锂 、 sodium dithionite 、 ammonium cerium(IV) nitrate 、 1,4-环己二烯 、 sodium hydride 作用下， 以 氘代苯 为溶剂， 反应 15.0h， 生成 1,2,3,4-tetrahydronaphthacene-6,11-quinone
  参考文献：
  名称：

  Arene 1,4-diradical formation from o-dialkynylarenes

  摘要：

  A series of five arene and quinone derivatives with dialkynyl substituents in the ortho positions and fixed in a 10-membered ring were prepared and tested with respect to thermal rearrangement to the corresponding arene 1,4 diradicals.

  DOI：

  10.1016/s0040-4039(00)92066-5

文献信息

• ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME
  申请人：Kim Kong Kyeom

  公开号：US20140077166A1

  公开（公告）日：2014-03-20

  The present invention provides an organic light emitting device comprising a first electrode, at least one organic layer and a second electrode, laminated successively, in which at least one layer of the organic layer has a polycyclic aromatic hydrocarbon as a core and comprises at least one of a derivative in which a substituted or unsubstituted C 2-30 cycloalkane, or a substituted or unsubstituted C 5-50 polycycloalkane is directly fused to the core or fused to a substituent of the core: and a new organic compound usable in the organic light emitting device. Furthermore, the present invention provides a charge carrier extracting, injecting or transporting material which has a polycyclic aromatic hydrocarbon as a core and comprises a derivative in which a substituted or unsubstituted C 2-30 cycloalkane, or a substituted or unsubstituted C 5-50 polycycloalkane is directly fused to the core or fused to a substituent of the core.

  本发明提供了一种有机发光器件，包括依次层叠的第一电极、至少一个有机层和第二电极，其中有机层中的至少一层具有多环芳烃作为核心，并包括以下至少一种衍生物：其中取代或未取代的C2-30环烷烃，或取代或未取代的C5-50多环烷烃直接与核心融合或与核心的取代基融合；以及一种新的可用于有机发光器件的有机化合物。此外，本发明提供了一种具有多环芳烃作为核心并包括以下衍生物的电荷载体提取、注入或传输材料：其中取代或未取代的C2-30环烷烃，或取代或未取代的C5-50多环烷烃直接与核心融合或与核心的取代基融合。
• [EN] HYDROXYBENZENE DERIVATIVES HAVING A N-ARYL SUBSTITUTE IMINO GROUP AND USE THEREOF IN THE TREATMENT OF SOLID TUMOURS<br/>[FR] DÉRIVÉS D'HYDROXYBENZÈNE COMPORTANT UN GROUPE IMINO À SUBSTITUTION N-ARYLE ET LEUR UTILISATION DANS LE TRAITEMENT DE TUMEURS SOLIDES
  申请人：UNIV DEGLI STUDI DI SALERNO

  公开号：WO2018116158A1

  公开（公告）日：2018-06-28

  The present invention relates to new compounds having hydroxyl, imino and carboxylic functionalities, processes for the production thereof and use thereof as antitumour agents for the treatment of solid tumours.

  本发明涉及具有羟基、亚胺基和羧基功能的新化合物，其生产过程以及将其用作抗肿瘤药物治疗实体肿瘤的用途。
• Cyclopentadienylcobalt-Mediated Intermolecular Cycloaddition of α,ω-Diynes to (Cyclo)alkenes: Synthesis of Linearly Fused Oligocycles and Extension to Enantiomerically Pure (6aR,10aR)-Dihydroanthracyclinones
  作者：K. Vollhardt、Corinne Aubert、Vincent Gandon、Sangdon Han、Barry Johnson、Max Malacria、Sten Schömenauer、Glenn Whitener

  DOI：10.1055/s-0029-1220007

  日期：2010.7

  The generality of the [CpCoL2]-mediated [2+2+2] cycloaddition of α,ω-diynes to (cyclo)alkenes has been extended to include linear oligocycles as models for the one-step, A + D → ABCD construction of optically pure, novel 6,10-dihydroanthracyclinones.

  [CpCoL2]介导的α,ω-二炔与（环）烯烃的[2+2+2]环加成反应的一般性已扩展至包括线性寡环模型，用于一步构建光学纯的全新6,10-二氢蒽环醌。
• Action of Phenylmagnesium Bromide on Anthraquinones. II
  作者：C. F. H. Allen、Alan Bell

  DOI：10.1021/ja01866a042

  日期：1940.9

  This preliminary report of the action of phenylmagnesium bromide on anthraquinone contains the description of a procedure for avoiding the recovery of large amounts of unchanged quinone, with consequent increasing of the yield. Butyl ether is preferable to toluene for "forced" Grignard reactions.

  这份关于苯基溴化镁对蒽醌作用的初步报告描述了避免回收大量未改变的醌从而提高产率的程序。对于“强制”格氏反应，丁醚优于甲苯。
• [EN] GROUP 3 METAL COMPOUNDS AND USE THEREOF IN THE TREATMENT OF SOLID TUMORS<br/>[FR] COMPOSÉS DE MÉTAL DU GROUPE 3 ET LEUR UTILISATION DANS LE TRAITEMENT DE TUMEURS SOLIDES
  申请人：UNIVERSITÀ DEGLI STUDI DI SALERNO

  公开号：WO2017191607A1

  公开（公告）日：2017-11-09

  The present invention relates to the compounds of Formula 1 wherein M is Sc or Y, Hal is CI, Br, F or I R is alkyl with 1 - 4 atoms of C X is CI, Br, F or I or a group such as that shown hereinafter wherein R is alkyl with 1 - 4 atoms of C and the use thereof in the treatment of solid tumors.

  本发明涉及公式1中的化合物，其中M是Sc或Y，Hal是Cl、Br、F或I，R是具有1-4个碳原子的烷基，X是Cl、Br、F或I，或者是如下所示的基团，其中R是具有1-4个碳原子的烷基，以及其在固体肿瘤治疗中的用途。