isopropyl hydrogen isopropylphosphonate | 249934-15-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: isopropyl hydrogen isopropylphosphonate
• 英文别名: Propan-2-yl(propan-2-yloxy)phosphinic acid
• CAS: 249934-15-4
• 化学式: C₆H₁₅O₃P
• 分子量: 166.157
• InChiKey: UXQZXLYZBXFOCY-UHFFFAOYSA-N

物化性质

• 沸点：
  222.6±23.0 °C(Predicted)
• 密度：
  1.062±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  1-[Chloro(propan-2-yl)phosphoryl]oxy-2-methylpropane 、 isopropyl hydrogen isopropylphosphonate 在 aluminum oxide 作用下， 反应 0.08h， 以94.6%的产率得到O-isobutyl-O'-isopropyl-P,P'-diisopropyl pyrophosphonate
  参考文献：
  名称：

  Surface Mediated Synthesis of Unsymmetrical O,O-dialkyl Alkyl Pyrophosphonates using Neutral Alumina: Potential Chemical Weapons Convention Related Compounds

  摘要：

  介绍了以 O-烷基烷基膦酸为原料，通过表面介导合成非对称 O,O'-二烷基烷基焦磷酸盐的方法。这些焦磷酸盐被列入《化学武器公约》（CWC）附表 2B4。此外，还研究了色谱级 Al2O3 的存在对一系列烷基膦酸磷化的影响。对于具有不同烷基的膦酸，观察到在 Al2O3 的存在下形成的受阻程度较高的焦磷酸盐的产率较高。与传统方法相比，该方法具有操作简便、反应时间短和产率高等优点。

  DOI：

  10.3184/030823408x318316
• 作为产物：
  描述：

  异丙基磷酸 、 异丙醇 在 苯胂酸 作用下， 生成 isopropyl hydrogen isopropylphosphonate
  参考文献：
  名称：

  Surface Mediated Synthesis of Unsymmetrical O,O-dialkyl Alkyl Pyrophosphonates using Neutral Alumina: Potential Chemical Weapons Convention Related Compounds

  摘要：

  介绍了以 O-烷基烷基膦酸为原料，通过表面介导合成非对称 O,O'-二烷基烷基焦磷酸盐的方法。这些焦磷酸盐被列入《化学武器公约》（CWC）附表 2B4。此外，还研究了色谱级 Al2O3 的存在对一系列烷基膦酸磷化的影响。对于具有不同烷基的膦酸，观察到在 Al2O3 的存在下形成的受阻程度较高的焦磷酸盐的产率较高。与传统方法相比，该方法具有操作简便、反应时间短和产率高等优点。

  DOI：

  10.3184/030823408x318316

文献信息

• Reactions of phosphonamidic acids and phosphonamidothioic acids with alcohols: mechanistic differences revealed by differing responses to steric effects
  作者：Martin J. P. Harger、Cherylin Preston

  DOI：10.1039/b307206a

  日期：——

  The formation of RP(X)(OH)OR′ (R = Pri or But, R′ = Me or Pri) from RP(X)(OH)NHBut and R′OH in CDCl3 is insensitive to steric effects when X = S but not when X = O (>103 times slower with R = But, R′ = Pri than with R = Pri, R′ = Me), pointing to a dissociative elimination–addition mechanism (metathiophosphonate intermediate) when X = S but an associative SN2(P) mechanism when X = O.

  在 CDCl3 中，当 X = S 时，RP(X)(OH)OR′（R = Pri 或 But，R′ = Me 或 Pri）与 RP(X)(OH)NHBut 和 R′OH 的形成对立体效应不敏感，但当 X = O 时则不然（R = But 时比 R = Pri，R′ = Me 时慢 >103 倍）、R′ = Pri 时比 R = Pri, R′ = Me 时慢 103 倍以上），这表明当 X = S 时，存在离解消除-加成机制（偏硫代磷酸酯中间体），而当 X = O 时，存在缔合 SN2(P) 机制。
• Heat stable alkaline proteases produced by a bacillus
  申请人：GENEX CORPORATION

  公开号：EP0220921A2

  公开（公告）日：1987-05-06

  Novel enzymes exhibiting proteolytic activity in alkaline media and stability at high temperatures and under alkaline conditions are produced by a novel Ba­cillus strain designated GX6638 or its mutants or var­iants. These enzymes are especially well-suited for inclusion in washing compositions. A culture of GX6638 has been deposited with the American Type Cul­ture Collection, Rockville, Maryland as ATCC No. 53278.

  一种名为 GX6638 的新型芽孢杆菌菌株或其突变体或变种产生了新型酶，这种酶在碱性介质中具有蛋白水解活性，并在高温和碱性条件下具有稳定性。这些酶特别适合加入洗涤组合物中。GX6638 的培养物已作为 ATCC 编号 53278 存放在马里兰州罗克维尔的美国类型培养物保藏中心。
• Process for the preparation of lactic acid-based polyester compositions
  申请人：DAINIPPON INK AND CHEMICALS, INC.

  公开号：EP0765913A1

  公开（公告）日：1997-04-02

  The present invention provides a process for the preparation of a biodegradable lactic acid-based polyester composition excellent in thermal stability, storage stability, flexibility, heat resistance, mechanical and physical properties and moldability which comprises kneading a lactic acid-based polyester and a polyester consisting of dicarboxylic acid component(s) and diol component(s) with a chelating agent, an acidic phosphoric acid ester, a molecular weight increasing agent, etc., and then devolatilizing the kneaded mixture. The present invention also provides a molding process of the foregoing lactic acid-based polyester composition. A process for the preparation of a lactic acid-based polyester composition is provided, which comprises melt-kneading a lactic acid-based polyester (A), a polyester (B) consisting of dicarboxylic acid component(s) and diol component(s) and a chelating agent and/or acidic phosphoric acid ester (C) in an amount such that the weight ratio (A)/(B) is from 99/1 to 10/90 and the proportion of (C) is 0.001 to 5 parts by weight based on 100 parts by weight of the sum of (A) and (B). A process for molding a lactic acid-based polyester composition is also provided, which comprises kneading a lactic acid-based polyester (A) and a polyester (B) consisting of dicarboxylic acid component(s) and diol component(s) with a chelating agent and/or acidic phosphoric acid ester (C), and then molding the material.

  本发明提供了一种在热稳定性、储存稳定性、柔韧性、耐热性、机械和物理性能以及成型性方面具有优异性能的可生物降解的乳酸基聚酯组合物的制备工艺，该工艺包括将乳酸基聚酯和由二羧酸组分和二元醇组分组成的聚酯与螯合剂、酸性磷酸酯、分子量增加剂等进行捏合，然后将捏合后的混合物脱胶。本发明还提供了前述乳酸基聚酯组合物的成型工艺。本发明提供了一种乳酸基聚酯组合物的制备工艺，该工艺包括熔融捏合乳酸基聚酯 (A)、由二羧酸组分和二元醇组分组成的聚酯 (B) 以及螯合剂和/或酸性磷酸酯 (C)，其用量使得(A)/(B)的重量比为 99/1 至 10/90，(C)的比例为 0.001至5份重量比，以100份重量比的(A)和(B)之和为基准。还提供了一种成型乳酸基聚酯组合物的工艺，包括将乳酸基聚酯（A）和由二羧酸组分和二元醇组分组成的聚酯（B）与螯合剂和/或酸性磷酸酯（C）捏合，然后将材料成型。
• FIRE-RESISTANT THERMOPLASTIC POLYURETHANE ELASTOMER COMPOSITION
  申请人：Adeka Corporation

  公开号：EP3135729A1

  公开（公告）日：2017-03-01

  The flame-retardant thermoplastic polyurethane elastomer composition of the present invention includes a thermoplastic polyurethane elastomer, (A) a (poly)phosphate compound represented by general formula (1), (B) a (poly)phosphate compound represented by general formula (3), and (C) silicon dioxide. The composition preferably contains (D) zinc oxide. Symbols n, X1, and p in formula (1) and r, Y1, and q in formula (3) are as defined in the description.

  本发明的阻燃性热塑性聚氨酯弹性体组合物包括热塑性聚氨酯弹性体、(A) 通式(1)代表的(多)磷酸化合物、(B) 通式(3)代表的(多)磷酸化合物和(C) 二氧化硅。组合物最好含有 (D) 氧化锌。式（1）中的符号 n、X1 和 p 以及式（3）中的符号 r、Y1 和 q 如说明中所定义。
• Light-emitting device and method for producing same
  申请人：Sumitomo Chemical Company, Limited

  公开号：US10711091B2

  公开（公告）日：2020-07-14

  Provided is a light-emitting device including an anode, a light-emitting layer, an electron-transporting layer and a cathode. The electron-transporting layer contains at least one electron-transporting material whose LUMO level is −3.0 eV or more and at least one dopant material selected from the group consisting of a heterocyclic compound whose SOMO level is −2.2 to −1.5 eV and a derivative thereof. The LUMO level of the electron-transporting material is smaller than the SOMO level of the heterocyclic compound.

  本发明提供了一种发光器件，包括阳极、发光层、电子传输层和阴极。电子传输层包含至少一种电子传输材料，其 LUMO 水平为 -3.0 eV 或更高，以及至少一种掺杂材料，该掺杂材料选自由 SOMO 水平为 -2.2 至 -1.5 eV 的杂环化合物及其衍生物组成的组。电子传输材料的 LUMO 电平小于杂环化合物的 SOMO 电平。