1-Brom-2-n-butylnaphthalin | 39131-73-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1-Brom-2-n-butylnaphthalin
• 英文别名: 1-bromo-2-butylnaphthalene
• CAS: 39131-73-2
• 化学式: C₁₄H₁₅Br
• 分子量: 263.177
• InChiKey: WXQJDPTVEWBKRL-UHFFFAOYSA-N

物化性质

• 沸点：
  342.9±11.0 °C(Predicted)
• 密度：
  1.280±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-Brom-2-n-butylnaphthalin 在 溴 、 sodium acetate 、 吡啶盐酸盐 、 溶剂黄146 作用下， 以 甲醇 为溶剂， 生成 (2-Butyl-naphthalen-1-yl)-(3,5-dibromo-4-hydroxy-phenyl)-methanone
  参考文献：
  名称：

  Goldenberg,C. et al., Chimica Therapeutica, 1972, vol. 7, p. 369 - 377

  摘要：

  DOI：
• 作为产物：
  描述：

  2-丁基萘 在 溴 作用下， 以 四氯化碳 为溶剂， 生成 1-Brom-2-n-butylnaphthalin
  参考文献：
  名称：

  Goldenberg,C. et al., Chimica Therapeutica, 1972, vol. 7, p. 369 - 377

  摘要：

  DOI：

文献信息

• Highly Chemo-, Regio- and <i>E/Z</i>-Selective Intermolecular Heck-Type Dearomative [2 + 2 + 1] Spiroannulation of Alkyl Bromoarenes with Internal Alkynes
  作者：Xingrong Liao、Deping Wang、Yueyuan Huang、Yudong Yang、Jingsong You

  DOI：10.1021/acs.orglett.9b00099

  日期：2019.2.15

  bromoarenes with internal alkynes. Challenges in this spiroannulation include the chemoselectivity among [2 + 2 + 1], [2 + 2 + 2], and [3 + 2] annulations and the E/Z-selectivity associated with the generated exocyclic double bond. In the presence of Pd(OAc)2 and a phosphine ligand, a variety of highly functionalized spirocyclopentadienes with an exocyclic carbon–carbon double bond are provided in good to excellent

  本文描述了烷基溴芳烃与内部炔烃的钯催化脱芳香环化。这种螺环化的挑战包括[2 + 2 + 1]，[2 + 2 + 2]和[3 + 2]环空中的化学选择性以及与生成的环外双键相关的E / Z选择性。在存在Pd（OAc）2和膦配体的情况下，可以提供各种具有环外碳-碳双键的高官能度螺环戊二烯，并具有优异的化学收率，区域选择性和E / Z选择性，并具有很高的收率。 Heck型途径。
• Method for producing an aromatic compound having an alkyl group with at least three carbon atoms
  申请人：TORAY INDUSTRIES, INC.

  公开号：EP0985649A2

  公开（公告）日：2000-03-15

  Aromatic compounds having an alkyl group with at least 3 carbon atoms are produced in a process comprising at least one of the following steps: (1) a step of contacting a starting material that contains an aromatic compound having a branched alkyl group with at least 3 carbon atoms, with a zeolite-containing catalyst in a liquid phase in the presence of hydrogen therein, thereby changing the position of the carbon atoms of the alkyl group bonding to the aromatic ring of the compound; (2) a step of contacting a starting material that contains an aromatic compound having a branched alkyl group with at least 3 carbon atoms, with a catalyst containing zeolite and containing rhenium and/or silver, in a liquid phase, thereby changing the position of the carbon atoms of the alkyl group bonding to the aromatic ring of the compound; (3) a step of contacting a halogenated aromatic compound having an alkyl group with at least 3 carbon atoms, with an acid-type catalyst, thereby isomerizing the compound; and (4) a step of treating a mixture of isomers of an aromatic compound having an alkyl group with at least 3 carbon atoms, with a zeolite adsorbent that contains at least one exchangable cation selected from alkali metals, alkaline earth metals, lead, thallium and silver, thereby separating a specific isomer from the isomer mixture through adsorption.

  具有至少 3 个碳原子烷基的芳香族化合物的生产工艺至少包括以下一个步骤： (1) 将含有至少 3 个碳原子的支链烷基的芳香族化合物的起始原料在液相中与含沸石的催化剂在氢存在的情况下接触，从而改变烷基的碳原子与化合物的芳香环键合的位置； (2) 将含有芳香族化合物的起始原料与含沸石和含铼和/或银的催化剂在液相中接触，该芳香族化合物具有至少 3 个碳原子的支链烷基，从而改变烷基碳原子与化合物芳香环键合的位置； (3) 将具有至少 3 个碳原子的烷基的卤代芳香族化合物与酸型催化剂接触，从而使该化合物异构化；以及 (4) 用沸石吸附剂处理具有至少 3 个碳原子的烷基的芳香族化合物的异构体混合物，该沸石吸附剂含有至少一种选自碱金属、碱土金属、铅、铊和银的可交换阳离子，从而通过吸附从异构体混合物中分离出特定的异构体。
• CuX2-mediated [4+2] benzannulation as a new synthetic tool for stereoselective construction of haloaromatic compounds
  作者：Yukie Isogai、Menggenbateer、F. Nawaz Khan、Naoki Asao

  DOI：10.1016/j.tet.2009.09.061

  日期：2009.11

  The CuX2-mediated reaction of enynal units, including ortho-alkynylbenzaldehydes, with alkynes gives a variety of haloaromatic compounds stereoselectively in good to high yields. 2,2'-Binaphthyl skeletons are also readily prepared by the reaction of ortho-alkynylbenzaldehydes and diynes. The method was applied to the synthesis of poly-substituted tetracene derivatives (C) 2009 Elsevier Ltd. All rights reserved
• US3989746A
  申请人：——

  公开号：US3989746A

  公开（公告）日：1976-11-02
• US4076746A
  申请人：——

  公开号：US4076746A

  公开（公告）日：1978-02-28