2-aminophenoxazin-3-one | 927803-99-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶嗪类
• 英文名称: 2-aminophenoxazin-3-one
• 英文别名: 2-Amino-4,4A-dihydro-3H-phenoxazin-3-one；2-amino-4,4a-dihydrophenoxazin-3-one
• CAS: 927803-99-4
• 化学式: C₁₂H₁₀N₂O₂
• 分子量: 214.224
• InChiKey: SEKIHKGMIWNOJB-UHFFFAOYSA-N

物化性质

• 沸点：
  375.9±42.0 °C(Predicted)
• 密度：
  1.47±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  64.7
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-氨基苯酚 在 [(1,2-(C₄H₈)]-salen-Co(II) complex 氧气 、 sodium iodide 作用下， 以 1,4-二氧六环 为溶剂， 120.0 ℃ 、6.0 MPa 条件下， 反应 2.0h， 以92%的产率得到2-aminophenoxazin-3-one
  参考文献：
  名称：

  Synthesis of 2-oxazolidinones by salen-Co-complexes catalyzed oxidative carbonylation of β-amino alcohols

  摘要：

  2-Oxazolidinones are synthesized in high yield by oxidative carbonylation of beta-amino alcohols using salen-Co(II)/NaI or salen-Co(III)-I as a catalyst and using CO as the carbonyl source. Studies of functional group compatibility using a series of substituted salen-Co(II) or salen-Co(III)-I complexes demonstrate a broad tolerance of functionality during the carbonylation reaction. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.12.028

文献信息

• Synthesis of 2-oxazolidinones by salen-Co-complexes catalyzed oxidative carbonylation of β-amino alcohols
  作者：Jian-Ming Liu、Xin-Gao Peng、Jian-Hua Liu、Shu-Zhan Zheng、Wei Sun、Chun-Gu Xia

  DOI：10.1016/j.tetlet.2006.12.028

  日期：2007.2

  2-Oxazolidinones are synthesized in high yield by oxidative carbonylation of beta-amino alcohols using salen-Co(II)/NaI or salen-Co(III)-I as a catalyst and using CO as the carbonyl source. Studies of functional group compatibility using a series of substituted salen-Co(II) or salen-Co(III)-I complexes demonstrate a broad tolerance of functionality during the carbonylation reaction. (c) 2006 Elsevier Ltd. All rights reserved.