Decafluor-1--piperidin | 311-92-2

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Decafluor-1--piperidin
• 英文别名: Perfluor-N-butylpiperidin；perfluoro-(1-butylpiperidine)；decafluoro-1-nonafluorobutyl-piperidine；perfluoro (N-butylpiperidine)；2,2,3,3,4,4,5,5,6,6-Decafluoro-1-(1,1,2,2,3,3,4,4,4-nonafluorobutyl)piperidine
• CAS: 311-92-2
• 化学式: C₉F₁₉N
• 分子量: 483.075
• InChiKey: QRGKREXBRIWEMS-UHFFFAOYSA-N

物化性质

• 沸点：
  113.3±40.0 °C(Predicted)
• 密度：
  1.82±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.8
• 重原子数：
  29
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  20

反应信息

• 作为反应物：
  描述：

  三氯化铝 、 Decafluor-1--piperidin 以 四氯化碳 为溶剂， 生成
  参考文献：
  名称：

  Plashkin, V. S.; Pushkina, L. N.; Sokolov, S. V., Zhurnal Organicheskoi Khimii, 1974, vol. 10, p. 1225 - 1233

  摘要：

  DOI：
• 作为产物：
  描述：

  1-丁基哌啶 、 氢氟酸 以 氢氟酸 为溶剂， 以43%的产率得到Decafluor-1--piperidin
  参考文献：
  名称：

  Mazalov, S. A.; Gerasimov, S. I.; Sokolov, S. V., Zhurnal Obshchei Khimii, 1965, vol. 35, p. 484 - 488

  摘要：

  DOI：

文献信息

• Perfusate for preserving organ to be transplanted and preserving method
  申请人：The Green Cross Corporation

  公开号：EP0033402A1

  公开（公告）日：1981-08-12

  An organ to be transplanted, such as a kidney, can effectively be preserved for an increased period of time by perfusion using a perfusate which is made of a Ringer's solution modified by increasing its potassium ion content to 8-20 meq/liter with a stably emulsified perfluorocarbon compound and dissolved albumin. A preferred concentration of the perfluorocarbon compound, for example perfluorodecalin, is 7.5 to 12.5%(W/V) and that of albumin is 1-8%(W/V) based on the perfusate.

  灌注液是由林格氏溶液改良而成，改良后的林格氏溶液将钾离子含量提高到 8-20 meq/升，并加入了稳定乳化的全氟碳化合物和溶解的白蛋白。全氟碳化合物（例如全氟萘烷）的优选浓度为 7.5-12.5%(W/V)，白蛋白的优选浓度为灌流液的 1-8%(W/V)。
• A nutritive emulsion having oxygen-transporting properties, and process for its preparation
  申请人：Kabi Pharmacia AB

  公开号：EP0220153A1

  公开（公告）日：1987-04-29

  An emulsion of perfluorocarbon compounds in an aqueous system has oxygen transporting properties. By incorpora­tion of fat of animal or vegetable origin and at least one of the amino acids glycine, serine or phenylalanine, or urea in the emulsion, the stability of the emulsion will be increased to a point where it can be sterilized by autoclaving, and have nutritive properties as well. The invention also concerns the preparation of an emulsion stabilized in the above manner.

  全氟碳化合物在水体系中的乳液具有氧气传输特性。通过在乳液中加入动物或植物脂肪以及甘氨酸、丝氨酸或苯丙氨酸中的至少一种氨基酸或尿素，乳液的稳定性将提高到可以通过高压灭菌消毒的程度，并具有营养特性。本发明还涉及以上述方式稳定乳剂的制备。
• Concentrated stable fluorchemical aqueous emulsions
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP0282949A2

  公开（公告）日：1988-09-21

  A stable concentrated aqueous emulsion of perfluorochemical, a phos­pholipid and a triglyceride of fatty acids has been demonstrated which has enhanced stability, diminished particle size and heightened tolerance by biological systems. The emulsion has utility as an oxygen transport medium, such as artificial blood. The emulsion can optionally include addition emulsifiers of SURFYNOL®SE surfactant and PLURONIC® P-105 surfactant. The emulsion is produced using an improved emul­sification technique.

  一种由全氟化学品、磷脂和脂肪酸甘油三酯组成的稳定浓缩水乳液已经得到证实，它具有更高的稳定性、更小的粒径和更强的生物系统耐受性。这种乳液可用作氧气运输介质，如人造血液。乳液中还可添加 SURFYNOL®SE 表面活性剂和 PLURONIC® P-105 表面活性剂等乳化剂。该乳液采用改进的乳化技术制成。
• Method for curing an organic coating using condensation heating and radiant energy
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0323061A2

  公开（公告）日：1989-07-05

  Coatings are cured by simultaneous exposure to radiant energy and condensing inert perfluoro­chemical vapors. The invention also includes an apparatus for use in curing coatings having a vessel (10) with reservoir (5) filled with inert perfluorochemical liquid (4), heated by heater (2). Cooling coils (13) and (14), for condensing perfluorochemical vapors (6), are located in the inlet (11) and outlet (12) of the vessel (10). A coating (8) on a substrate (7) is carried through the vessel (10) on a continuously moving belt (15). The coating (8) is cured by vapors (6) and radiant energy from energy source (9) passing through windows (16).

  涂层是通过同时暴露于辐射能和冷凝惰性全氟化合物蒸汽而固化的。本发明还包括一种用于固化涂层的设备，该设备具有一个容器（10），容器（10）的储液器（5）中装有惰性全氟化合物液体（4），由加热器（2）加热。冷却线圈（13）和（14）位于容器（10）的入口（11）和出口（12），用于冷凝全氟化合物蒸汽（6）。基材 (7) 上的涂层 (8) 通过连续移动的传送带 (15) 穿过容器 (10)。涂层 (8) 在蒸汽 (6) 和来自能源 (9) 的辐射能作用下通过窗口 (16) 固化。
• Process for rapid thawing and storage of frozen fluorocarbon emulsion, and resultant product
  申请人：ALPHA THERAPEUTIC CORPORATION

  公开号：EP0548601A1

  公开（公告）日：1993-06-30

  A method for rapidly preparing a frozen fluorocarbon emulsion for administration without degradation and having an extended shelf life is disclosed.

  本发明公开了一种快速制备冷冻碳氟化合物乳剂的方法，该乳剂可在不降解的情况下给药，并具有较长的保质期。