diethyl 3,4-diphenylhexanedioate | 79912-78-0

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• 英文名称: diethyl 3,4-diphenylhexanedioate
• 英文别名: meso-β,β'-Diphenyl-adipinsaeure-diaethylester；meso-3,4-diphenyl-adipic acid diethyl ester；meso-3,4-Diphenyl-adipinsaeure-diaethylester；3,4-Diphenyl-adipinsaeure-diaethylester；diethyl (3S,4R)-3,4-diphenylhexanedioate
• CAS: 79912-78-0
• 化学式: C₂₂H₂₆O₄
• 分子量: 354.446
• InChiKey: ZTLVOOMDEJJVLD-BGYRXZFFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  26
• 可旋转键数：
  11
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  3-苯丙酸乙酯 在 二叔丁基过氧化物 作用下， 生成 diethyl 3,4-diphenylhexanedioate
  参考文献：
  名称：

  172.取代基对游离烷基的相对稳定作用。第四部分 自由叔胺的选择性氢吸收。-丁氧基自由基

  摘要：

  DOI：

  10.1039/jr9580000891

文献信息

• Electrolytic Reduction of Aromatic Carboxylic Acids. II. Electrolytic Reduction of Cinnamic Acid
  作者：Shin-ichi Ono、Tadao Hayashi

  DOI：10.1246/bcsj.26.11

  日期：1953.1

  The electrolytic reduction of cinnamic acid at a Pb, a Hg, a Hg-Zn or a Pt-Pt cathode in acid solution was studied. It was found that the formation of bimolecular compounds depended on the nature of cathode materials and the condition of the reduction. It was confirmed that the γ-phenylpropyl alcohol could not be produced by the electrolytic reduction of cinnamic acid. It was found that the reduction

  研究了肉桂酸在 Pb、Hg、Hg-Zn 或 Pt-Pt 阴极在酸溶液中的电解还原。发现双分子化合物的形成取决于正极材料的性质和还原条件。确认肉桂酸电解还原不能生成γ-苯丙醇。发现肉桂酸在 Pt-Pt 阴极还原得到环己基丙酸。讨论了高压氢气在还原过程中的作用。
• Salkind, Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1914, vol. 46, p. 497
  作者：Salkind

  DOI：——

  日期：——
• Knunjanz; Wjasankin, Doklady Akademii Nauk SSSR, 1957, vol. 113, p. 112
  作者：Knunjanz、Wjasankin

  DOI：——

  日期：——
• Wilson, Transactions of the Electrochemical Society, 1947, vol. 92, p. 369,372
  作者：Wilson

  DOI：——

  日期：——
• Csp³–Csp³ Homocoupling Reaction of Benzyl Halides Catalyzed by Rhodium
  作者：Kazuyuki Sato、Yuichi Inoue、Tomohisa Mori、Atsushi Sakaue、Atsushi Tarui、Masaaki Omote、Itsumaro Kumadaki、Akira Ando

  DOI：10.1021/ol501619w

  日期：2014.7.18

  A highly reactive alkylrhodium complex was formed from Me2Zn and RhCl(PPh3)(3) and effectively catalyzed a Csp(3)-Csp(3) homocoupling reaction of benzyl halides. A Csp(3)-Csp(3) coupling reaction using Rh catalyst has not been reported up to now. The reaction proceeded under very mild conditions and gave the corresponding homocoupling products even if they had reactive substituents such as an uncovered formyl or hydroxymethyl group.